Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 43804..44281 Replicon chromosome
Accession NZ_CP117967
Organism Veillonella rogosae strain AC2811 AN NA

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PT376_RS00210 Protein ID WP_274204665.1
Coordinates 44015..44281 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID E4LDZ1
Locus tag PT376_RS00205 Protein ID WP_009352129.1
Coordinates 43804..44025 (+) Length 74 a.a.

Genomic Context

PT376_RS00185PT376_RS00190PT376_RS00195PT376_RS00200PT376_RS00205PT376_RS00210PT376_RS00215PT376_RS00220PT376_RS00230PT376_RS00235PT376_RS00225
Location: 40042..40932 (891 bp)
Type: Others
Protein ID: WP_274204661.1
Location: 40990..41871 (882 bp)
Type: Others
Protein ID: WP_274204662.1
Location: 41858..42676 (819 bp)
Type: Others
Protein ID: WP_274204663.1
Location: 42676..43419 (744 bp)
Type: Others
Protein ID: WP_274204664.1
Location: 43804..44025 (222 bp)
Type: Antitoxin
Protein ID: WP_009352129.1
Location: 44015..44281 (267 bp)
Type: Toxin
Protein ID: WP_274204665.1
Location: 44292..44504 (213 bp)
Type: Others
Protein ID: WP_009352194.1
Location: 44571..45656 (1086 bp)
Type: Others
Protein ID: WP_274204666.1
Location: 46790..47593 (804 bp)
Type: Others
Protein ID: WP_009351987.1
Location: 47605..48543 (939 bp)
Type: Others
Protein ID: WP_274204668.1
Location: 45758..46549 (792 bp)
Type: Others
Protein ID: WP_274204667.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PT376_RS0018540042..40932+891WP_274204661.1phosphate ABC transporter substrate-binding protein-
PT376_RS0019040990..41871+882WP_274204662.1phosphate ABC transporter permease subunit PstC-
PT376_RS0019541858..42676+819WP_274204663.1ABC transporter permease subunit-
PT376_RS0020042676..43419+744WP_274204664.1ATP-binding cassette domain-containing protein-
PT376_RS0020543804..44025+222WP_009352129.1DUF6290 family proteinAntitoxin
PT376_RS0021044015..44281+267WP_274204665.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PT376_RS0021544292..44504+213WP_009352194.1hypothetical protein-
PT376_RS0022044571..45656+1086WP_274204666.1hypothetical protein-
PT376_RS0022545758..46549-792WP_274204667.1carbon-nitrogen family hydrolase-
PT376_RS0023046790..47593+804WP_009351987.1polysaccharide deacetylase family protein-
PT376_RS0023547605..48543+939WP_274204668.1phosphodiester glycosidase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10501.13 Da        Isoelectric Point: 10.5370

>T272568 WP_274204665.1 NZ_CP117967:44015-44281 [Veillonella rogosae]
MAYKLEFSKRFDKQFSKLDKSTQRYLFNWLIKNVDNVENPRYSGKSLTGNKTGLWRYRIGNHRVIADINGYRCIILALEV
GHRKDIYK

Download         Length: 267 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8500.65 Da        Isoelectric Point: 4.1835

>AT272568 WP_009352129.1 NZ_CP117967:43804-44025 [Veillonella rogosae]
MANISVRLNEQEEELFKTYAEFMDETLSTLFKKALLEKIEDEFDLKVGQKALAEYEQDPVTYSVAEMRAKYGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2S7YYS4

References