Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 43804..44281 Replicon chromosome
Accession NZ_CP117967
Organism Veillonella rogosae strain AC2811 AN NA

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PT376_RS00210 Protein ID WP_274204665.1
Coordinates 44015..44281 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID E4LDZ1
Locus tag PT376_RS00205 Protein ID WP_009352129.1
Coordinates 43804..44025 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT376_RS00185 40042..40932 + 891 WP_274204661.1 phosphate ABC transporter substrate-binding protein -
PT376_RS00190 40990..41871 + 882 WP_274204662.1 phosphate ABC transporter permease subunit PstC -
PT376_RS00195 41858..42676 + 819 WP_274204663.1 ABC transporter permease subunit -
PT376_RS00200 42676..43419 + 744 WP_274204664.1 ATP-binding cassette domain-containing protein -
PT376_RS00205 43804..44025 + 222 WP_009352129.1 DUF6290 family protein Antitoxin
PT376_RS00210 44015..44281 + 267 WP_274204665.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PT376_RS00215 44292..44504 + 213 WP_009352194.1 hypothetical protein -
PT376_RS00220 44571..45656 + 1086 WP_274204666.1 hypothetical protein -
PT376_RS00225 45758..46549 - 792 WP_274204667.1 carbon-nitrogen family hydrolase -
PT376_RS00230 46790..47593 + 804 WP_009351987.1 polysaccharide deacetylase family protein -
PT376_RS00235 47605..48543 + 939 WP_274204668.1 phosphodiester glycosidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10501.13 Da        Isoelectric Point: 10.5370

>T272568 WP_274204665.1 NZ_CP117967:44015-44281 [Veillonella rogosae]
MAYKLEFSKRFDKQFSKLDKSTQRYLFNWLIKNVDNVENPRYSGKSLTGNKTGLWRYRIGNHRVIADINGYRCIILALEV
GHRKDIYK

Download         Length: 267 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8500.65 Da        Isoelectric Point: 4.1835

>AT272568 WP_009352129.1 NZ_CP117967:43804-44025 [Veillonella rogosae]
MANISVRLNEQEEELFKTYAEFMDETLSTLFKKALLEKIEDEFDLKVGQKALAEYEQDPVTYSVAEMRAKYGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2S7YYS4

References