Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 2273896..2274437 Replicon chromosome
Accession NZ_CP117963
Organism Faecalibacterium prausnitzii strain AP34BHI

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PT301_RS10950 Protein ID WP_118551719.1
Coordinates 2274162..2274437 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PT301_RS10945 Protein ID WP_118551721.1
Coordinates 2273896..2274165 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT301_RS10925 2269899..2270774 + 876 WP_274235909.1 ABC transporter permease -
PT301_RS10930 2270774..2271715 + 942 WP_118551725.1 ABC transporter permease -
PT301_RS10935 2271738..2272793 + 1056 WP_097792636.1 ABC transporter ATP-binding protein -
PT301_RS10940 2272786..2273727 + 942 WP_274235523.1 ATP-binding cassette domain-containing protein -
PT301_RS10945 2273896..2274165 + 270 WP_118551721.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PT301_RS10950 2274162..2274437 + 276 WP_118551719.1 type II toxin-antitoxin system YafQ family toxin Toxin
PT301_RS10955 2274530..2276056 - 1527 WP_118551717.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase -
PT301_RS10960 2276178..2276948 - 771 WP_097792639.1 triose-phosphate isomerase -
PT301_RS10965 2277039..2278247 - 1209 WP_118551715.1 phosphoglycerate kinase -
PT301_RS10970 2278499..2278702 - 204 WP_097792641.1 PTS ascorbate transporter subunit IIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-72)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10835.54 Da        Isoelectric Point: 8.0414

>T272565 WP_118551719.1 NZ_CP117963:2274162-2274437 [Faecalibacterium prausnitzii]
MKYEIKPSSRFKKDMKLVKKRGYDPRLIETVIKTLANGEPLDKKYRDHILVGDYSGFHECHITPDWLLIYQIYDEELYLL
LSRTGTHSDLF

Download         Length: 276 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10327.78 Da        Isoelectric Point: 4.3164

>AT272565 WP_118551721.1 NZ_CP117963:2273896-2274165 [Faecalibacterium prausnitzii]
MTTLNIPIDEKVEKEAEELFSDFGLDIPTAVNIFLRQSIRENCIPFNIEREVPNADTIAAMREAEEMKKHPEKYKGYHDV
DEMMKDLLA

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References