Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4233457..4233728 Replicon chromosome
Accession NZ_CP117962
Organism Escherichia coli strain JM109

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4233587..4233690 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4233457..4233728 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT299_RS21670 4230012..4230674 - 663 WP_000944256.1 exodeoxyribonuclease X -
PT299_RS21675 4230698..4231354 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
PT299_RS21680 4231456..4231686 - 231 WP_000916763.1 DNA polymerase III subunit theta -
PT299_RS21685 4231825..4232199 + 375 WP_000168747.1 CopC domain-containing protein YobA -
PT299_RS21690 4232203..4233075 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
PT299_RS21695 4233088..4233429 + 342 WP_000976476.1 YebY family protein -
- 4233457..4233728 - 272 - - Antitoxin
- 4233587..4233690 + 104 - - Toxin
PT299_RS21700 4233825..4234481 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
PT299_RS21705 4234482..4234673 - 192 WP_000457842.1 YebW family protein -
PT299_RS21710 4234778..4235014 - 237 WP_001295499.1 YebV family protein -
PT299_RS21715 4235132..4236571 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T272560 NZ_CP117962:4233587-4233690 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT272560 NZ_CP117962:c4233728-4233457 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References