272474

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1275869..1276786 Replicon chromosome
Accession NZ_CP117945
Organism Bacillus velezensis strain ZY1

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag PT966_RS06720 Protein ID WP_072588210.1
Coordinates 1276040..1276786 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag PT966_RS06715 Protein ID WP_003154807.1
Coordinates 1275869..1276039 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT966_RS06675 (PT966_06675) 1271100..1272722 + 1623 WP_003154821.1 pyocin knob domain-containing protein -
PT966_RS06680 (PT966_06680) 1272735..1273106 + 372 WP_014304856.1 XkdW family protein -
PT966_RS06685 (PT966_06685) 1273112..1273309 + 198 WP_003154819.1 XkdX family protein -
PT966_RS06690 (PT966_06690) 1273366..1274127 + 762 WP_046559521.1 hypothetical protein -
PT966_RS06695 (PT966_06695) 1274179..1274442 + 264 WP_003154815.1 hemolysin XhlA family protein -
PT966_RS06700 (PT966_06700) 1274456..1274719 + 264 WP_003154813.1 phage holin -
PT966_RS06705 (PT966_06705) 1274733..1275611 + 879 WP_014304858.1 N-acetylmuramoyl-L-alanine amidase -
PT966_RS06710 (PT966_06710) 1275647..1275772 - 126 WP_003154809.1 hypothetical protein -
PT966_RS06715 (PT966_06715) 1275869..1276039 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
PT966_RS06720 (PT966_06720) 1276040..1276786 - 747 WP_072588210.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
PT966_RS06725 (PT966_06725) 1276891..1277889 - 999 WP_003154805.1 inorganic phosphate transporter -
PT966_RS06730 (PT966_06730) 1277902..1278519 - 618 WP_003154804.1 DUF47 domain-containing protein -
PT966_RS06735 (PT966_06735) 1278805..1280121 - 1317 WP_003154801.1 amino acid permease -
PT966_RS06740 (PT966_06740) 1280445..1281395 + 951 WP_024085196.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29033.52 Da        Isoelectric Point: 4.7755

>T272474 WP_072588210.1 NZ_CP117945:c1276786-1276040 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVVGAMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYGEKMNVTASL
CNYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQDRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT272474 WP_003154807.1 NZ_CP117945:c1276039-1275869 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References