Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4730267..4730859 Replicon chromosome
Accession NZ_CP117886
Organism Serratia ureilytica strain KML.E1

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag PTZ17_RS22465 Protein ID WP_089197523.1
Coordinates 4730509..4730859 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag PTZ17_RS22460 Protein ID WP_089197522.1
Coordinates 4730267..4730515 (+) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTZ17_RS22440 (PTZ17_22440) 4726085..4726423 + 339 WP_025304525.1 PTS lactose/cellobiose transporter subunit IIA -
PTZ17_RS22445 (PTZ17_22445) 4726420..4727727 + 1308 WP_033645265.1 6-phospho-beta-glucosidase -
PTZ17_RS22450 (PTZ17_22450) 4727800..4728780 + 981 WP_033645266.1 LacI family DNA-binding transcriptional regulator -
PTZ17_RS22455 (PTZ17_22455) 4728972..4730156 + 1185 WP_060660175.1 MFS transporter TsgA -
PTZ17_RS22460 (PTZ17_22460) 4730267..4730515 + 249 WP_089197522.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PTZ17_RS22465 (PTZ17_22465) 4730509..4730859 + 351 WP_089197523.1 type II toxin-antitoxin system ChpB family toxin Toxin
PTZ17_RS22470 (PTZ17_22470) 4730856..4732139 - 1284 WP_060441380.1 cytosine deaminase -
PTZ17_RS22475 (PTZ17_22475) 4732428..4734977 + 2550 WP_206195783.1 nitrite reductase large subunit NirB -
PTZ17_RS22480 (PTZ17_22480) 4734974..4735300 + 327 WP_019456155.1 nitrite reductase small subunit NirD -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-114)

Antitoxin

(6-49)


Sequences


Toxin        


Download         Length: 117 a.a.        Molecular weight: 12390.38 Da        Isoelectric Point: 11.5657

>T272470 WP_089197523.1 NZ_CP117886:4730509-4730859 [Serratia ureilytica]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFVERAPGEVIADALARLQAIID

Download         Length: 351 bp


Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9129.58 Da        Isoelectric Point: 4.5026

>AT272470 WP_089197522.1 NZ_CP117886:4730267-4730515 [Serratia ureilytica]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGTLVIKPVKKRYSLQQLLDSCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References