Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4185724..4186393 Replicon chromosome
Accession NZ_CP117886
Organism Serratia ureilytica strain KML.E1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PTZ17_RS19920 Protein ID WP_016929976.1
Coordinates 4185724..4186146 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag PTZ17_RS19925 Protein ID WP_004931679.1
Coordinates 4186127..4186393 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTZ17_RS19900 (PTZ17_19900) 4181613..4182131 + 519 WP_033635825.1 flavodoxin FldB -
PTZ17_RS19905 (PTZ17_19905) 4182169..4183533 - 1365 WP_033652165.1 cell envelope integrity protein CreD -
PTZ17_RS19910 (PTZ17_19910) 4183614..4185032 - 1419 WP_160204551.1 two-component system sensor histidine kinase CreC -
PTZ17_RS19915 (PTZ17_19915) 4185029..4185724 - 696 WP_047573795.1 two-component system response regulator CreB -
PTZ17_RS19920 (PTZ17_19920) 4185724..4186146 - 423 WP_016929976.1 protein YgfX Toxin
PTZ17_RS19925 (PTZ17_19925) 4186127..4186393 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
PTZ17_RS19930 (PTZ17_19930) 4186714..4187706 + 993 WP_176589383.1 tRNA-modifying protein YgfZ -
PTZ17_RS19935 (PTZ17_19935) 4187745..4188242 - 498 WP_110147385.1 DUF2165 domain-containing protein -
PTZ17_RS19940 (PTZ17_19940) 4188393..4189067 - 675 WP_033644772.1 hemolysin III family protein -
PTZ17_RS19945 (PTZ17_19945) 4189251..4189859 + 609 WP_004931670.1 HD domain-containing protein -
PTZ17_RS19950 (PTZ17_19950) 4189900..4190826 - 927 WP_176589382.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16501.62 Da        Isoelectric Point: 11.2159

>T272468 WP_016929976.1 NZ_CP117886:c4186146-4185724 [Serratia ureilytica]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLHPPAGNGEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT272468 WP_004931679.1 NZ_CP117886:c4186393-4186127 [Serratia ureilytica]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References