Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 182113..182583 Replicon chromosome
Accession NZ_CP117886
Organism Serratia ureilytica strain KML.E1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PTZ17_RS00820 Protein ID WP_240324795.1
Coordinates 182359..182583 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PTZ17_RS00815 Protein ID WP_223524348.1
Coordinates 182113..182313 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTZ17_RS00785 (PTZ17_00785) 177306..178574 + 1269 WP_103101689.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
PTZ17_RS00790 (PTZ17_00790) 178571..179770 + 1200 WP_033652425.1 anaerobic glycerol-3-phosphate dehydrogenase subunit GlpC -
PTZ17_RS00795 (PTZ17_00795) 179805..180368 - 564 WP_129993498.1 DcrB family lipoprotein -
PTZ17_RS00800 (PTZ17_00800) 180449..180883 - 435 WP_060660071.1 GNAT family N-acetyltransferase -
PTZ17_RS00805 (PTZ17_00805) 180925..181584 - 660 WP_033652423.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
PTZ17_RS00810 (PTZ17_00810) 181806..182051 + 246 WP_025304890.1 sulfurtransferase TusA -
PTZ17_RS00815 (PTZ17_00815) 182113..182313 + 201 WP_223524348.1 stability determinant Antitoxin
PTZ17_RS00820 (PTZ17_00820) 182359..182583 + 225 WP_240324795.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PTZ17_RS00825 (PTZ17_00825) 182643..184961 - 2319 WP_103101686.1 zinc/cadmium/mercury/lead-transporting ATPase -
PTZ17_RS00830 (PTZ17_00830) 185642..187105 + 1464 WP_033644999.1 serralysin family metalloprotease -
PTZ17_RS00835 (PTZ17_00835) 187160..187537 + 378 WP_025304893.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-73)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8670.25 Da        Isoelectric Point: 11.6785

>T272459 WP_240324795.1 NZ_CP117886:182359-182583 [Serratia ureilytica]
VGFIANDNPLAARKMKVLIMEAVTPAARHPRIFRRGRVDGTHEIPLHPHYLLIYQVLETHIRVLRVLHTRRQYP

Download         Length: 225 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7526.59 Da        Isoelectric Point: 4.1359

>AT272459 WP_223524348.1 NZ_CP117886:182113-182313 [Serratia ureilytica]
MMSILLLPTVAKMENEEHTQGYERWFLERVQEAMDEPWPGIPHDDVMAEMDAVIAAAEARINAKQA

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References