272454

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 1949716..1950266 Replicon chromosome
Accession NZ_CP117881
Organism Novosphingobium sp. KACC 22771

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PQ467_RS08885 Protein ID WP_274173087.1
Coordinates 1949964..1950266 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PQ467_RS08880 Protein ID WP_274173086.1
Coordinates 1949716..1949961 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQ467_RS08860 (PQ467_08860) 1945253..1946031 + 779 Protein_1743 SDR family oxidoreductase -
PQ467_RS08865 (PQ467_08865) 1946461..1948161 - 1701 WP_274173084.1 hypothetical protein -
PQ467_RS08870 (PQ467_08870) 1948164..1948541 - 378 WP_274173085.1 hypothetical protein -
PQ467_RS08875 (PQ467_08875) 1948878..1949515 - 638 Protein_1746 tyrosine-type recombinase/integrase -
PQ467_RS08880 (PQ467_08880) 1949716..1949961 + 246 WP_274173086.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PQ467_RS08885 (PQ467_08885) 1949964..1950266 + 303 WP_274173087.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PQ467_RS08890 (PQ467_08890) 1950641..1951096 + 456 WP_274173088.1 hypothetical protein -
PQ467_RS08895 (PQ467_08895) 1951463..1952809 + 1347 WP_274173089.1 hypothetical protein -
PQ467_RS08900 (PQ467_08900) 1952806..1953321 + 516 WP_274173090.1 hypothetical protein -
PQ467_RS08905 (PQ467_08905) 1953318..1955243 + 1926 WP_274173091.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1948164..1960660 12496


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Antitoxin ParD

(6-64)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11272.70 Da        Isoelectric Point: 4.8401

>T272454 WP_274173087.1 NZ_CP117881:1949964-1950266 [Novosphingobium sp. KACC 22771]
VPRFQLTRAAADDLTAIFLEGIEQFGLPQADAYHEGLSAIFAFLADYPHAARLREEISPPVRVHPYKAHLVIYDVGAEDE
VIILRVRHGREDWISSNFDG

Download         Length: 303 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9057.15 Da        Isoelectric Point: 4.7265

>AT272454 WP_274173086.1 NZ_CP117881:1949716-1949961 [Novosphingobium sp. KACC 22771]
MATMNISLPDPMKQWVEAQADTGRYSNASDYVRDLIRRDQERADKVSVMQRLIDEARASGLSDETMADIRARAISQAGLQ
A

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References