Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1267097..1267722 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag PSR30_RS05660 Protein ID WP_005976087.1
Coordinates 1267097..1267300 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID C6DB73
Locus tag PSR30_RS05665 Protein ID WP_005976089.1
Coordinates 1267354..1267722 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS05630 (PSR30_05630) 1262558..1262896 + 339 WP_002208627.1 P-II family nitrogen regulator -
PSR30_RS05635 (PSR30_05635) 1262936..1264222 + 1287 WP_039472387.1 ammonium transporter AmtB -
PSR30_RS05640 (PSR30_05640) 1264357..1265220 - 864 WP_010303014.1 acyl-CoA thioesterase II -
PSR30_RS05645 (PSR30_05645) 1265433..1266014 + 582 WP_010303016.1 YbaY family lipoprotein -
PSR30_RS05650 (PSR30_05650) 1266034..1266354 - 321 WP_010282239.1 MGMT family protein -
PSR30_RS05660 (PSR30_05660) 1267097..1267300 - 204 WP_005976087.1 HHA domain-containing protein Toxin
PSR30_RS05665 (PSR30_05665) 1267354..1267722 - 369 WP_005976089.1 Hha toxicity modulator TomB Antitoxin
PSR30_RS05670 (PSR30_05670) 1268321..1268464 - 144 WP_005976091.1 type B 50S ribosomal protein L36 -
PSR30_RS05675 (PSR30_05675) 1268482..1268730 - 249 WP_039472395.1 type B 50S ribosomal protein L31 -
PSR30_RS05680 (PSR30_05680) 1268961..1272089 - 3129 WP_274215013.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T272444 WP_005976087.1 NZ_CP117874:c1267300-1267097 [Pectobacterium carotovorum subsp. carotovorum]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT272444 WP_005976089.1 NZ_CP117874:c1267722-1267354 [Pectobacterium carotovorum subsp. carotovorum]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z3G5

References