Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 735701..736361 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PSR30_RS03315 Protein ID WP_010301815.1
Coordinates 735987..736361 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag PSR30_RS03310 Protein ID WP_005971623.1
Coordinates 735701..735967 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS03290 (PSR30_03290) 731603..732607 - 1005 WP_138254842.1 LacI family DNA-binding transcriptional regulator -
PSR30_RS03295 (PSR30_03295) 732662..733270 - 609 WP_274214817.1 HD domain-containing protein -
PSR30_RS03300 (PSR30_03300) 733549..734196 + 648 WP_039539856.1 hemolysin III family protein -
PSR30_RS03305 (PSR30_03305) 734464..735465 - 1002 WP_274214818.1 tRNA-modifying protein YgfZ -
PSR30_RS03310 (PSR30_03310) 735701..735967 + 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
PSR30_RS03315 (PSR30_03315) 735987..736361 + 375 WP_010301815.1 protein YgfX Toxin
PSR30_RS03320 (PSR30_03320) 736430..737365 + 936 WP_240819903.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
PSR30_RS03325 (PSR30_03325) 737431..737754 - 324 WP_010301820.1 hypothetical protein -
PSR30_RS03330 (PSR30_03330) 737783..738301 - 519 WP_010301821.1 flavodoxin FldB -
PSR30_RS03335 (PSR30_03335) 738641..739027 - 387 WP_039534581.1 thioesterase family protein -
PSR30_RS03340 (PSR30_03340) 739235..740563 - 1329 WP_274214819.1 MFS transporter -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-119)

Antitoxin

(8-79)


Sequences


Toxin        


Download         Length: 125 a.a.        Molecular weight: 14654.33 Da        Isoelectric Point: 10.5560

>T272443 WP_010301815.1 NZ_CP117874:735987-736361 [Pectobacterium carotovorum subsp. carotovorum]
MQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 375 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT272443 WP_005971623.1 NZ_CP117874:735701-735967 [Pectobacterium carotovorum subsp. carotovorum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References