Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 566662..567440 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag PSR30_RS02525 Protein ID WP_274214773.1
Coordinates 566952..567440 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag PSR30_RS02520 Protein ID WP_274214772.1
Coordinates 566662..566955 (+) Length 98 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS02490 (PSR30_02490) 561922..562707 + 786 WP_274214766.1 phosphonate metabolism protein PhnP -
PSR30_RS02495 (PSR30_02495) 563171..565000 + 1830 WP_274214767.1 P-loop NTPase fold protein -
PSR30_RS02500 (PSR30_02500) 565131..565373 - 243 Protein_483 type II toxin-antitoxin system CcdA family antitoxin -
PSR30_RS02505 (PSR30_02505) 565388..565636 - 249 WP_274214768.1 helix-turn-helix transcriptional regulator -
PSR30_RS02510 (PSR30_02510) 565721..565975 - 255 WP_274214770.1 helix-turn-helix transcriptional regulator -
PSR30_RS02515 (PSR30_02515) 566080..566322 + 243 WP_274214771.1 helix-turn-helix transcriptional regulator -
PSR30_RS02520 (PSR30_02520) 566662..566955 + 294 WP_274214772.1 DUF1778 domain-containing protein Antitoxin
PSR30_RS02525 (PSR30_02525) 566952..567440 + 489 WP_274214773.1 GNAT family N-acetyltransferase Toxin
PSR30_RS02530 (PSR30_02530) 567753..568637 + 885 WP_010299620.1 ParA family protein -
PSR30_RS02535 (PSR30_02535) 568634..569035 + 402 WP_274214774.1 hypothetical protein -
PSR30_RS02540 (PSR30_02540) 569528..570889 - 1362 WP_029368129.1 hypothetical protein -
PSR30_RS02545 (PSR30_02545) 571227..571973 - 747 WP_274214775.1 MobC family replication-relaxation protein -
PSR30_RS02550 (PSR30_02550) 572110..572280 + 171 WP_165572483.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 566406..575134 8728


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(76-143)

Antitoxin

(14-88)


Sequences


Toxin        


Download         Length: 163 a.a.        Molecular weight: 17458.25 Da        Isoelectric Point: 6.8526

>T272442 WP_274214773.1 NZ_CP117874:566952-567440 [Pectobacterium carotovorum subsp. carotovorum]
MISAPEPLHAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGAKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLVD
SL

Download         Length: 489 bp


Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10871.50 Da        Isoelectric Point: 10.1968

>AT272442 WP_274214772.1 NZ_CP117874:566662-566955 [Pectobacterium carotovorum subsp. carotovorum]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLTRLDQAPAPN
AALRKTMQTPAPWELKK

Download         Length: 294 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References