Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 566662..567440 | Replicon | chromosome |
Accession | NZ_CP117874 | ||
Organism | Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2 |
Toxin (Protein)
Gene name | TacT2 | Uniprot ID | - |
Locus tag | PSR30_RS02525 | Protein ID | WP_274214773.1 |
Coordinates | 566952..567440 (+) | Length | 163 a.a. |
Antitoxin (Protein)
Gene name | TacA2 | Uniprot ID | - |
Locus tag | PSR30_RS02520 | Protein ID | WP_274214772.1 |
Coordinates | 566662..566955 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PSR30_RS02490 (PSR30_02490) | 561922..562707 | + | 786 | WP_274214766.1 | phosphonate metabolism protein PhnP | - |
PSR30_RS02495 (PSR30_02495) | 563171..565000 | + | 1830 | WP_274214767.1 | P-loop NTPase fold protein | - |
PSR30_RS02500 (PSR30_02500) | 565131..565373 | - | 243 | Protein_483 | type II toxin-antitoxin system CcdA family antitoxin | - |
PSR30_RS02505 (PSR30_02505) | 565388..565636 | - | 249 | WP_274214768.1 | helix-turn-helix transcriptional regulator | - |
PSR30_RS02510 (PSR30_02510) | 565721..565975 | - | 255 | WP_274214770.1 | helix-turn-helix transcriptional regulator | - |
PSR30_RS02515 (PSR30_02515) | 566080..566322 | + | 243 | WP_274214771.1 | helix-turn-helix transcriptional regulator | - |
PSR30_RS02520 (PSR30_02520) | 566662..566955 | + | 294 | WP_274214772.1 | DUF1778 domain-containing protein | Antitoxin |
PSR30_RS02525 (PSR30_02525) | 566952..567440 | + | 489 | WP_274214773.1 | GNAT family N-acetyltransferase | Toxin |
PSR30_RS02530 (PSR30_02530) | 567753..568637 | + | 885 | WP_010299620.1 | ParA family protein | - |
PSR30_RS02535 (PSR30_02535) | 568634..569035 | + | 402 | WP_274214774.1 | hypothetical protein | - |
PSR30_RS02540 (PSR30_02540) | 569528..570889 | - | 1362 | WP_029368129.1 | hypothetical protein | - |
PSR30_RS02545 (PSR30_02545) | 571227..571973 | - | 747 | WP_274214775.1 | MobC family replication-relaxation protein | - |
PSR30_RS02550 (PSR30_02550) | 572110..572280 | + | 171 | WP_165572483.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 566406..575134 | 8728 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 163 a.a. Molecular weight: 17458.25 Da Isoelectric Point: 6.8526
>T272442 WP_274214773.1 NZ_CP117874:566952-567440 [Pectobacterium carotovorum subsp. carotovorum]
MISAPEPLHAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGAKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLVD
SL
MISAPEPLHAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGAKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLVD
SL
Download Length: 489 bp
Antitoxin
Download Length: 98 a.a. Molecular weight: 10871.50 Da Isoelectric Point: 10.1968
>AT272442 WP_274214772.1 NZ_CP117874:566662-566955 [Pectobacterium carotovorum subsp. carotovorum]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLTRLDQAPAPN
AALRKTMQTPAPWELKK
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLTRLDQAPAPN
AALRKTMQTPAPWELKK
Download Length: 294 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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