Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 477300..477883 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name parE Uniprot ID A0A7V8PTK4
Locus tag PSR30_RS02155 Protein ID WP_010296214.1
Coordinates 477578..477883 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7V8PT23
Locus tag PSR30_RS02150 Protein ID WP_010296210.1
Coordinates 477300..477590 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS02130 (PSR30_02130) 472434..473696 - 1263 WP_010296200.1 L-rhamnose isomerase -
PSR30_RS02135 (PSR30_02135) 473693..475183 - 1491 WP_010296202.1 rhamnulokinase -
PSR30_RS02140 (PSR30_02140) 475520..476359 + 840 WP_010296204.1 HTH-type transcriptional activator RhaS -
PSR30_RS02145 (PSR30_02145) 476384..477238 + 855 WP_039539617.1 helix-turn-helix domain-containing protein -
PSR30_RS02150 (PSR30_02150) 477300..477590 + 291 WP_010296210.1 ribbon-helix-helix protein, CopG family Antitoxin
PSR30_RS02155 (PSR30_02155) 477578..477883 + 306 WP_010296214.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSR30_RS02160 (PSR30_02160) 478003..479709 - 1707 WP_274214738.1 ABC transporter ATP-binding protein -
PSR30_RS02165 (PSR30_02165) 479706..480572 - 867 WP_040031931.1 ABC transporter permease -
PSR30_RS02170 (PSR30_02170) 480565..481524 - 960 WP_029367586.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11576.44 Da        Isoelectric Point: 9.8325

>T272441 WP_010296214.1 NZ_CP117874:477578-477883 [Pectobacterium carotovorum subsp. carotovorum]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTGRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11064.13 Da        Isoelectric Point: 4.7692

>AT272441 WP_010296210.1 NZ_CP117874:477300-477590 [Pectobacterium carotovorum subsp. carotovorum]
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8PTK4

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8PT23

References