Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 459212..460762 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag PSR30_RS02090 Protein ID WP_274214735.1
Coordinates 459464..460762 (+) Length 433 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag PSR30_RS02085 Protein ID WP_180782447.1
Coordinates 459212..459460 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS02060 (PSR30_02060) 455039..456382 + 1344 WP_274214731.1 HEAT repeat domain-containing protein -
PSR30_RS02065 (PSR30_02065) 456463..456747 + 285 WP_039507360.1 damage-inducible protein J -
PSR30_RS02070 (PSR30_02070) 456744..457049 + 306 WP_274214732.1 type II toxin-antitoxin system RelE/ParE family toxin -
PSR30_RS02075 (PSR30_02075) 457055..457846 - 792 WP_274214733.1 HNH endonuclease -
PSR30_RS02080 (PSR30_02080) 458000..459097 + 1098 WP_274214734.1 DUF1615 domain-containing protein -
PSR30_RS02085 (PSR30_02085) 459212..459460 + 249 WP_180782447.1 helix-turn-helix domain-containing protein Antitoxin
PSR30_RS02090 (PSR30_02090) 459464..460762 + 1299 WP_274214735.1 type II toxin-antitoxin system HipA family toxin Toxin
PSR30_RS02095 (PSR30_02095) 460899..462368 - 1470 WP_039499259.1 SulP family inorganic anion transporter -
PSR30_RS02100 (PSR30_02100) 462365..463033 - 669 WP_072012979.1 carbonic anhydrase -
PSR30_RS02105 (PSR30_02105) 463605..465554 - 1950 WP_274214736.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-398)

Antitoxin

Cro/C1-type helix-turn-helix domain

(10-64)


Sequences

Toxin        


Download         Length: 433 a.a.        Molecular weight: 48450.52 Da        Isoelectric Point: 7.2073

>T272440 WP_274214735.1 NZ_CP117874:459464-460762 [Pectobacterium carotovorum subsp. carotovorum]
MNILTVALNGIAVGALAKGVGSDMTFTYYPDWLSRPGARAISLSLPLQRATYRGDVVYNFFDNLLPDNDSIRSRIQARFR
IATKQPFDLLTSIGGDCVGAIQIYPVDTPVAPVTDVHAEALDNDEIEALLQGYREAPLGMATDREDFRISLAGAQEKTAL
LWYKNQWHRPQGNTPTSHIFKLPIGYIANNSIDLSDSVENEWLCLKIAEKYGFTVAQAEISRFNSQKVLIVERFDRRWSR
SDKPWLMRLPQEDFCQALGIAPALKYESDGGPGIEKSMALLLGSQQAMQDRDTFFKSQILFWMLAAIDGHAKNFSVFIEP
GSAYRMTPLYDVISAFPFMGPAGISVQKAKMAMAVLGRNRHFHWHKILPRHYFSSARQVGYPQERVAAMMSEMKANTERV
IAEVEALLPDDFPERISHPIFAGLRSQAARLP

Download         Length: 1299 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9363.58 Da        Isoelectric Point: 6.4835

>AT272440 WP_180782447.1 NZ_CP117874:459212-459460 [Pectobacterium carotovorum subsp. carotovorum]
MKITSAGMLAHAMRDERKKHKLNQSQVAESMGIKQSTVSDFENHPEGTRLETLFKLLAALDLELHLSKRGEQQAGQEWSE
EW

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References