272438

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 360477..361008 Replicon chromosome
Accession NZ_CP117874
Organism Pectobacterium carotovorum subsp. carotovorum strain ZJ-4-2

Toxin (Protein)


Gene name stbE Uniprot ID A0A7V8PTM5
Locus tag PSR30_RS01620 Protein ID WP_039470363.1
Coordinates 360721..361008 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A3R8PFZ6
Locus tag PSR30_RS01615 Protein ID WP_039470361.1
Coordinates 360477..360731 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR30_RS01590 (PSR30_01590) 355934..356524 - 591 WP_005975525.1 DnaA initiator-associating protein DiaA -
PSR30_RS01595 (PSR30_01595) 356588..356944 - 357 WP_274215411.1 YraN family protein -
PSR30_RS01600 (PSR30_01600) 356941..358959 - 2019 WP_039547218.1 penicillin-binding protein activator -
PSR30_RS01605 (PSR30_01605) 359021..359908 + 888 WP_039470360.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
PSR30_RS01615 (PSR30_01615) 360477..360731 + 255 WP_039470361.1 plasmid stabilization protein Antitoxin
PSR30_RS01620 (PSR30_01620) 360721..361008 + 288 WP_039470363.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSR30_RS01625 (PSR30_01625) 361185..361970 + 786 WP_039547220.1 4,5-DOPA dioxygenase extradiol -
PSR30_RS01630 (PSR30_01630) 362038..363198 - 1161 WP_010297418.1 glutathionylspermidine synthase family protein -
PSR30_RS01635 (PSR30_01635) 363209..363883 - 675 WP_010297420.1 DUF1190 family protein -
PSR30_RS01640 (PSR30_01640) 364150..365544 - 1395 WP_040031843.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10974.88 Da        Isoelectric Point: 10.6713

>T272438 WP_039470363.1 NZ_CP117874:360721-361008 [Pectobacterium carotovorum subsp. carotovorum]
MTYKLKFVPSALKEWKKLGHPVREQFKKKLVERLENPHVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9192.34 Da        Isoelectric Point: 3.7947

>AT272438 WP_039470361.1 NZ_CP117874:360477-360731 [Pectobacterium carotovorum subsp. carotovorum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
PDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8PTM5

Antitoxin

Source ID Structure
AlphaFold DB A0A3R8PFZ6

References