Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 54753..55423 Replicon plasmid pKOB3
Accession NZ_CP117862
Organism Komagataeibacter oboediens strain NCIB 8034

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LV478_RS18880 Protein ID WP_275879407.1
Coordinates 55001..55423 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LV478_RS18875 Protein ID WP_275879406.1
Coordinates 54753..55004 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV478_RS18850 (LV478_18865) 50434..50817 + 384 Protein_66 recombinase family protein -
LV478_RS18855 (LV478_18870) 50814..51593 + 780 WP_035979553.1 DUF4019 domain-containing protein -
LV478_RS18860 (LV478_18875) 52888..53124 + 237 WP_083824341.1 DUF4160 domain-containing protein -
LV478_RS18865 (LV478_18880) 53114..53521 + 408 WP_099542224.1 DUF2442 domain-containing protein -
LV478_RS18870 (LV478_18885) 53835..54077 + 243 WP_053324047.1 BrnA antitoxin family protein -
LV478_RS18875 (LV478_18890) 54753..55004 + 252 WP_275879406.1 plasmid stabilization protein Antitoxin
LV478_RS18880 (LV478_18895) 55001..55423 + 423 WP_275879407.1 type II toxin-antitoxin system VapC family toxin Toxin
LV478_RS18885 (LV478_18900) 55629..56360 - 732 WP_275879408.1 SprT family zinc-dependent metalloprotease -
LV478_RS18890 (LV478_18905) 56360..59662 - 3303 WP_275879409.1 HsdR family type I site-specific deoxyribonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..97332 97332


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15219.46 Da        Isoelectric Point: 4.3712

>T272431 WP_275879407.1 NZ_CP117862:55001-55423 [Komagataeibacter oboediens]
MILLDTNVISEPWKPVPEPCVLDWIDAQAIETLFLSAVTVAELRFGIGAMPAGRRQEVLQERLEQDVLPLFKGRILSFDL
GASQAYAELMVQARCEGRAIGKADGYIAATAASRGYAVASRDVSPFEAAGVRVLNPWEDA

Download         Length: 423 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9085.33 Da        Isoelectric Point: 6.4658

>AT272431 WP_275879406.1 NZ_CP117862:54753-55004 [Komagataeibacter oboediens]
MSSVVIRNLPEETHRALKAQAVLHGRNAEAEIRTILEAAVRPQQRVRLGSLLAAIGREAGVSEQDVTALQVRDQTPAEPM
SFE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References