Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3033..3703 Replicon plasmid pKOB3
Accession NZ_CP117862
Organism Komagataeibacter oboediens strain NCIB 8034

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LV478_RS18545 Protein ID WP_275879407.1
Coordinates 3281..3703 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LV478_RS18540 Protein ID WP_275879433.1
Coordinates 3033..3284 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV478_RS18525 (LV478_18540) 1168..1404 + 237 WP_083824341.1 DUF4160 domain-containing protein -
LV478_RS18530 (LV478_18545) 1394..1801 + 408 WP_099542224.1 DUF2442 domain-containing protein -
LV478_RS18535 (LV478_18550) 2115..2357 + 243 WP_053324047.1 BrnA antitoxin family protein -
LV478_RS18540 (LV478_18555) 3033..3284 + 252 WP_275879433.1 plasmid stabilization protein Antitoxin
LV478_RS18545 (LV478_18560) 3281..3703 + 423 WP_275879407.1 type II toxin-antitoxin system VapC family toxin Toxin
LV478_RS18550 (LV478_18565) 3909..4640 - 732 WP_275879434.1 SprT family zinc-dependent metalloprotease -
LV478_RS18555 (LV478_18570) 4640..7942 - 3303 WP_275879409.1 HsdR family type I site-specific deoxyribonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..97332 97332


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15219.46 Da        Isoelectric Point: 4.3712

>T272426 WP_275879407.1 NZ_CP117862:3281-3703 [Komagataeibacter oboediens]
MILLDTNVISEPWKPVPEPCVLDWIDAQAIETLFLSAVTVAELRFGIGAMPAGRRQEVLQERLEQDVLPLFKGRILSFDL
GASQAYAELMVQARCEGRAIGKADGYIAATAASRGYAVASRDVSPFEAAGVRVLNPWEDA

Download         Length: 423 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9088.34 Da        Isoelectric Point: 6.4658

>AT272426 WP_275879433.1 NZ_CP117862:3033-3284 [Komagataeibacter oboediens]
MSSVVIRNLPEETHRALKAQAVLHGRSTEAEIRTILEAAVRPQQRVRLGSLLAAIGREAGVSEQDVTALQVRDQTPAEPM
SFE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References