Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 109669..110269 Replicon plasmid pKOB1
Accession NZ_CP117859
Organism Komagataeibacter oboediens strain NCIB 8034

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LV478_RS01505 Protein ID WP_130732983.1
Coordinates 109669..110013 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LV478_RS01510 Protein ID WP_130732982.1
Coordinates 110006..110269 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV478_RS01480 (LV478_01485) 105820..106029 - 210 Protein_103 recombinase family protein -
LV478_RS01485 (LV478_01490) 106222..106962 + 741 Protein_104 OB-fold nucleic acid binding domain-containing protein -
LV478_RS01490 (LV478_01495) 107403..107510 - 108 WP_275877900.1 helix-turn-helix domain-containing protein -
LV478_RS01495 (LV478_01500) 107686..109029 - 1344 WP_034926246.1 IS1380 family transposase -
LV478_RS01500 (LV478_01505) 109101..109604 - 504 WP_275877901.1 recombinase family protein -
LV478_RS01505 (LV478_01510) 109669..110013 - 345 WP_130732983.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LV478_RS01510 (LV478_01515) 110006..110269 - 264 WP_130732982.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LV478_RS01515 (LV478_01520) 110331..110519 - 189 WP_130732981.1 hypothetical protein -
LV478_RS01520 (LV478_01525) 110697..111056 - 360 WP_248705407.1 hypothetical protein -
LV478_RS01525 (LV478_01530) 111181..111623 + 443 Protein_112 IS5 family transposase -
LV478_RS01535 (LV478_01540) 113202..114218 - 1017 WP_275877902.1 IS110 family transposase -
LV478_RS01540 (LV478_01545) 114299..114616 + 318 Protein_115 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..259334 259334
- inside IScluster/Tn - - 94802..114616 19814


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13277.17 Da        Isoelectric Point: 10.2205

>T272425 WP_130732983.1 NZ_CP117859:c110013-109669 [Komagataeibacter oboediens]
MTEYAIEFDDRALREWDGLDGSIRRKFEKKLEKLVLNPHSPGNELHGDLAGFYKIKLRRDGYRLVYQVVEQRIVIFVIAV
GRREDNEIYTAATKRVPETPADRTKPSSGKSRKR

Download         Length: 345 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9615.01 Da        Isoelectric Point: 7.3200

>AT272425 WP_130732982.1 NZ_CP117859:c110269-110006 [Komagataeibacter oboediens]
MSAVTFRVDDALKSAAVAKLSAHGLSLSDVLRDTLAYIAETGQPPVKRRLVTDEDARLIEVVRERLADPAPRHRMTLAEL
KARHPDD

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References