Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2138437..2138605 Replicon chromosome
Accession NZ_CP117853
Organism Klebsiella michiganensis strain 2020CK-00215

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2138495..2138598 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2138437..2138605 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUO96_RS10140 (PUO96_10140) 2133564..2135624 + 2061 WP_033836507.1 oligopeptidase B -
PUO96_RS10145 (PUO96_10145) 2135631..2136290 - 660 WP_014229839.1 exodeoxyribonuclease X -
PUO96_RS10150 (PUO96_10150) 2136369..2136599 - 231 WP_004103351.1 DNA polymerase III subunit theta -
PUO96_RS10155 (PUO96_10155) 2136735..2137109 + 375 WP_014229838.1 CopC domain-containing protein YobA -
PUO96_RS10160 (PUO96_10160) 2137114..2137983 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
PUO96_RS10165 (PUO96_10165) 2138000..2138338 + 339 WP_004103344.1 YebY family protein -
- 2138437..2138605 - 169 - - Antitoxin
- 2138495..2138598 + 104 - - Toxin
PUO96_RS10170 (PUO96_10170) 2138723..2139682 - 960 WP_042945476.1 spore coat protein U domain-containing protein -
PUO96_RS10175 (PUO96_10175) 2139697..2142027 - 2331 WP_064405637.1 fimbria/pilus outer membrane usher protein -
PUO96_RS10180 (PUO96_10180) 2142030..2142794 - 765 WP_049082702.1 fimbria/pilus periplasmic chaperone -
PUO96_RS10185 (PUO96_10185) 2142813..2143331 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T272415 NZ_CP117853:2138495-2138598 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT272415 NZ_CP117853:c2138605-2138437 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References