Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 428378..429038 Replicon chromosome
Accession NZ_CP117851
Organism Salmonella enterica subsp. enterica serovar Mbandaka strain SM_B30R

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag PTZ67_RS02095 Protein ID WP_000244755.1
Coordinates 428378..428791 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag PTZ67_RS02100 Protein ID WP_000351186.1
Coordinates 428772..429038 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTZ67_RS02075 (424319) 424319..426052 - 1734 WP_000813392.1 single-stranded-DNA-specific exonuclease RecJ -
PTZ67_RS02080 (426058) 426058..426771 - 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PTZ67_RS02085 (426795) 426795..427691 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
PTZ67_RS02090 (427804) 427804..428325 + 522 WP_017441091.1 flavodoxin FldB -
PTZ67_RS02095 (428378) 428378..428791 - 414 WP_000244755.1 protein YgfX Toxin
PTZ67_RS02100 (428772) 428772..429038 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
PTZ67_RS02105 (429288) 429288..430268 + 981 WP_017441090.1 tRNA-modifying protein YgfZ -
PTZ67_RS02110 (430384) 430384..431043 - 660 WP_000250289.1 hemolysin III family protein -
PTZ67_RS02115 (431207) 431207..431518 - 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
PTZ67_RS02120 (431676) 431676..433109 + 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T272364 WP_000244755.1 NZ_CP117851:c428791-428378 [Salmonella enterica subsp. enterica serovar Mbandaka]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT272364 WP_000351186.1 NZ_CP117851:c429038-428772 [Salmonella enterica subsp. enterica serovar Mbandaka]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References