Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1834106..1834766 Replicon chromosome
Accession NZ_CP117850
Organism Salmonella enterica subsp. enterica serovar Mbandaka strain SM_F22R

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag PTZ65_RS09020 Protein ID WP_000244755.1
Coordinates 1834353..1834766 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag PTZ65_RS09015 Protein ID WP_000351186.1
Coordinates 1834106..1834372 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTZ65_RS08995 (1830035) 1830035..1831468 - 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -
PTZ65_RS09000 (1831626) 1831626..1831937 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
PTZ65_RS09005 (1832101) 1832101..1832760 + 660 WP_000250289.1 hemolysin III family protein -
PTZ65_RS09010 (1832876) 1832876..1833856 - 981 WP_017441090.1 tRNA-modifying protein YgfZ -
PTZ65_RS09015 (1834106) 1834106..1834372 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
PTZ65_RS09020 (1834353) 1834353..1834766 + 414 WP_000244755.1 protein YgfX Toxin
PTZ65_RS09025 (1834819) 1834819..1835340 - 522 WP_017441091.1 flavodoxin FldB -
PTZ65_RS09030 (1835453) 1835453..1836349 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
PTZ65_RS09035 (1836373) 1836373..1837086 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PTZ65_RS09040 (1837092) 1837092..1838825 + 1734 WP_000813392.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T272348 WP_000244755.1 NZ_CP117850:1834353-1834766 [Salmonella enterica subsp. enterica serovar Mbandaka]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT272348 WP_000351186.1 NZ_CP117850:1834106-1834372 [Salmonella enterica subsp. enterica serovar Mbandaka]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References