Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 89431..89938 Replicon chromosome
Accession NZ_CP117825
Organism Fusobacterium nucleatum strain FNP

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PSC67_RS00415 Protein ID WP_274180392.1
Coordinates 89678..89938 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag PSC67_RS00410 Protein ID WP_274180391.1
Coordinates 89431..89685 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSC67_RS00410 (PSC67_00410) 89431..89685 + 255 WP_274180391.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PSC67_RS00415 (PSC67_00415) 89678..89938 + 261 WP_274180392.1 Txe/YoeB family addiction module toxin Toxin
PSC67_RS00420 (PSC67_00420) 89948..90452 + 505 Protein_83 GNAT family N-acetyltransferase -
PSC67_RS00425 (PSC67_00425) 90480..90968 + 489 WP_274180393.1 GNAT family protein -
PSC67_RS00430 (PSC67_00430) 90965..91615 + 651 WP_274180394.1 endonuclease III -
PSC67_RS00435 (PSC67_00435) 91694..92890 + 1197 WP_005895386.1 cysteine desulfurase NifS -
PSC67_RS00440 (PSC67_00440) 92953..93339 + 387 WP_005895388.1 Fe-S cluster assembly scaffold protein NifU -
PSC67_RS00445 (PSC67_00445) 93422..94702 + 1281 WP_274180395.1 D-alanyl-D-alanine carboxypeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10283.81 Da        Isoelectric Point: 9.3654

>T272323 WP_274180392.1 NZ_CP117825:89678-89938 [Fusobacterium nucleatum]
MTNLVWTHKAWQDYLYWQTQDKKTLKKINELVKDIERNGALNGIGKPEVLKNESAYSRRIDEKNRLVYRIVDGFIWIIAC
KGHYEE

Download         Length: 261 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9810.14 Da        Isoelectric Point: 4.4346

>AT272323 WP_274180391.1 NZ_CP117825:89431-89685 [Fusobacterium nucleatum]
MLAINYTTLRTNLKSYFDKAVDNDEDIIITRKNERNVVLLSLDKYNEFLKAMRNLEYMTKIREGIAELEAGKGEIHDLIE
VDDD

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References