Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-DUF971
Location 1275927..1276532 Replicon chromosome
Accession NZ_CP117821
Organism Xylella fastidiosa strain ICMP 8731

Toxin (Protein)


Gene name PumA Uniprot ID B2I5N3
Locus tag PT013_RS05775 Protein ID WP_004089252.1
Coordinates 1275927..1276223 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PT013_RS05780 Protein ID WP_004089254.1
Coordinates 1276227..1276532 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT013_RS05750 (PT013_05750) 1271092..1272069 + 978 WP_004087353.1 hypothetical protein -
PT013_RS05755 (PT013_05755) 1272328..1272774 + 447 WP_004087355.1 hypothetical protein -
PT013_RS05760 (PT013_05760) 1272878..1274122 - 1245 WP_011097983.1 tail fiber protein -
PT013_RS05765 (PT013_05765) 1274126..1274686 - 561 WP_011097869.1 DUF2612 domain-containing protein -
PT013_RS05770 (PT013_05770) 1274683..1275828 - 1146 WP_011097984.1 baseplate J/gp47 family protein -
PT013_RS05775 (PT013_05775) 1275927..1276223 + 297 WP_004089252.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PT013_RS05780 (PT013_05780) 1276227..1276532 + 306 WP_004089254.1 putative addiction module antidote protein Antitoxin
PT013_RS05785 (PT013_05785) 1276543..1276896 - 354 WP_011097986.1 hypothetical protein -
PT013_RS05790 (PT013_05790) 1276893..1277534 - 642 WP_004090764.1 Gp138 family membrane-puncturing spike protein -
PT013_RS05795 (PT013_05795) 1277531..1278361 - 831 WP_004090766.1 hypothetical protein -
PT013_RS05800 (PT013_05800) 1278358..1278675 - 318 WP_011097873.1 hypothetical protein -
PT013_RS05805 (PT013_05805) 1278675..1279445 - 771 WP_004090769.1 hypothetical protein -
PT013_RS05810 (PT013_05810) 1279556..1279783 + 228 WP_004091377.1 DUF6290 family protein -
PT013_RS05815 (PT013_05815) 1279767..1280033 + 267 WP_011097988.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1272878..1315792 42914


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-95)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10790.57 Da        Isoelectric Point: 10.0509

>T272308 WP_004089252.1 NZ_CP117821:1275927-1276223 [Xylella fastidiosa]
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKD

Download         Length: 297 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10983.37 Da        Isoelectric Point: 5.0941

>AT272308 WP_004089254.1 NZ_CP117821:1276227-1276532 [Xylella fastidiosa]
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMS

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A060HBK9

Antitoxin

Source ID Structure

References