Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2524338..2525021 Replicon chromosome
Accession NZ_CP117820
Organism Xylella fastidiosa strain ICMP 8740

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PT012_RS11340 Protein ID WP_004086858.1
Coordinates 2524338..2524766 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PT012_RS11345 Protein ID WP_004086856.1
Coordinates 2524767..2525021 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT012_RS11310 (PT012_11310) 2520892..2521653 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
PT012_RS11335 (PT012_11335) 2522854..2524248 + 1395 WP_272819586.1 hypothetical protein -
PT012_RS11340 (PT012_11340) 2524338..2524766 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
PT012_RS11345 (PT012_11345) 2524767..2525021 - 255 WP_004086856.1 hypothetical protein Antitoxin
PT012_RS11350 (PT012_11350) 2525146..2525688 + 543 WP_071870032.1 hypothetical protein -
PT012_RS11355 (PT012_11355) 2526009..2526382 - 374 Protein_2211 DUF596 domain-containing protein -
PT012_RS11360 (PT012_11360) 2526394..2526699 - 306 WP_228762248.1 DUF769 domain-containing protein -
PT012_RS11365 (PT012_11365) 2526898..2527290 - 393 WP_038211775.1 DUF596 domain-containing protein -
PT012_RS11370 (PT012_11370) 2527301..2527558 - 258 WP_021358680.1 hemagglutinin -
PT012_RS11375 (PT012_11375) 2527832..2528215 - 384 WP_004086848.1 DUF596 domain-containing protein -
PT012_RS11380 (PT012_11380) 2528220..2529257 - 1038 WP_004086846.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T272302 WP_004086858.1 NZ_CP117820:c2524766-2524338 [Xylella fastidiosa]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT272302 WP_004086856.1 NZ_CP117820:c2525021-2524767 [Xylella fastidiosa]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References