Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1028235..1028989 Replicon chromosome
Accession NZ_CP117820
Organism Xylella fastidiosa strain ICMP 8740

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag PT012_RS04685 Protein ID WP_021358673.1
Coordinates 1028235..1028714 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PT012_RS04690 Protein ID WP_004085396.1
Coordinates 1028717..1028989 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT012_RS04660 (PT012_04660) 1023492..1024928 + 1437 WP_027700685.1 exodeoxyribonuclease I -
PT012_RS04665 (PT012_04665) 1024925..1025611 + 687 WP_012337799.1 TIGR02453 family protein -
PT012_RS04670 (PT012_04670) 1025742..1026740 + 999 WP_004085391.1 MBL fold metallo-hydrolase -
PT012_RS04675 (PT012_04675) 1026715..1026789 + 75 Protein_899 hypothetical protein -
PT012_RS04680 (PT012_04680) 1026835..1027899 + 1065 WP_080654483.1 toprim domain-containing protein -
PT012_RS04685 (PT012_04685) 1028235..1028714 - 480 WP_021358673.1 GNAT family N-acetyltransferase Toxin
PT012_RS04690 (PT012_04690) 1028717..1028989 - 273 WP_004085396.1 DUF1778 domain-containing protein Antitoxin
PT012_RS04695 (PT012_04695) 1029341..1030246 - 906 WP_004085395.1 AEC family transporter -
PT012_RS04700 (PT012_04700) 1030362..1030980 + 619 Protein_904 IS607 family transposase -
PT012_RS04705 (PT012_04705) 1031208..1033241 + 2034 WP_234545896.1 glycoside hydrolase family 3 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(33-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17645.42 Da        Isoelectric Point: 9.9283

>T272296 WP_021358673.1 NZ_CP117820:c1028714-1028235 [Xylella fastidiosa]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Download         Length: 480 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10264.77 Da        Isoelectric Point: 5.0488

>AT272296 WP_004085396.1 NZ_CP117820:c1028989-1028717 [Xylella fastidiosa]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References