Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2665656..2667112 Replicon chromosome
Accession NZ_CP117818
Organism Legionella pneumophila strain D5916

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag PT257_RS11855 Protein ID WP_062725383.1
Coordinates 2665656..2666507 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag PT257_RS11860 Protein ID WP_062725381.1
Coordinates 2666504..2667112 (-) Length 203 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT257_RS11840 (PT257_11840) 2661803..2664019 - 2217 WP_062725449.1 copper-translocating P-type ATPase -
PT257_RS11845 (PT257_11845) 2664302..2664463 + 162 WP_154699017.1 hypothetical protein -
PT257_RS11850 (PT257_11850) 2664669..2665523 + 855 WP_136696918.1 GGDEF domain-containing protein -
PT257_RS11855 (PT257_11855) 2665656..2666507 - 852 WP_062725383.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
PT257_RS11860 (PT257_11860) 2666504..2667112 - 609 WP_062725381.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
PT257_RS11865 (PT257_11865) 2667562..2670033 - 2472 WP_284647207.1 P-loop NTPase fold protein -
PT257_RS11870 (PT257_11870) 2670126..2671508 - 1383 WP_284647208.1 HD domain-containing protein -
PT257_RS11875 (PT257_11875) 2671828..2672112 - 285 WP_284647209.1 TraK family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-259)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(9-56)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31902.98 Da        Isoelectric Point: 7.9767

>T272290 WP_062725383.1 NZ_CP117818:c2666507-2665656 [Legionella pneumophila]
MTKNIGESLRSRLKNIAVKEGSDFNAVLTRYGLERMLYRIGESEYSNQFLLKGALLFNLWYDMPHRPTKDIDLLGFGDND
MAYIKQTFSKICSISADDGISFLSESVTVNTIKKDGGYTGARVELFGELAKAKIKIQIDIGYGDAVTPRPIDAHYPVLLS
DLPAPKIRTYPIYTVIAEKLHAIAFLGMANSRLKDYLDLYVLLNNEQLDNQILAKAIQATFNRRGMTLPEALPIGLTDEF
ANDPTRESMWKAFLRKNELEQKSLTEVIVVIRNLILMPFALAK

Download         Length: 852 bp

Antitoxin


Download         Length: 203 a.a.        Molecular weight: 22947.90 Da        Isoelectric Point: 9.7451

>AT272290 WP_062725381.1 NZ_CP117818:c2667112-2666504 [Legionella pneumophila]
MKTEATYKQKVLQMASKTGIVRMSDLTKRGITRATISRLVSENKLEKLASGLYCLPETEFSEKESLIIIASRVPKAVFCL
LTALQIHELTTQLPRKVWIAMPKGSHTPKMDYPPVKMVQYSDEAFSEGIEIIDSDNIKLRVYNLAKTIADSFKHRNKIGL
DVAIEALKEAYSKNKVTVDELWHYAKICRVANVMRPYIEAIQ

Download         Length: 609 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References