Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2706718..2708174 Replicon chromosome
Accession NZ_CP117814
Organism Legionella pneumophila strain D5241

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag PT258_RS12040 Protein ID WP_062725383.1
Coordinates 2706718..2707569 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag PT258_RS12045 Protein ID WP_062725381.1
Coordinates 2707566..2708174 (-) Length 203 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT258_RS12030 (PT258_12030) 2704525..2705763 - 1239 WP_062724776.1 IS256 family transposase -
PT258_RS12035 (PT258_12035) 2705881..2706585 + 705 WP_062740838.1 GGDEF domain-containing protein -
PT258_RS12040 (PT258_12040) 2706718..2707569 - 852 WP_062725383.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
PT258_RS12045 (PT258_12045) 2707566..2708174 - 609 WP_062725381.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
PT258_RS12050 (PT258_12050) 2708699..2709874 - 1176 WP_061784407.1 ISL3-like element ISLpn11 family transposase -
PT258_RS12055 (PT258_12055) 2709955..2710143 - 189 Protein_2364 ISL3 family transposase -
PT258_RS12060 (PT258_12060) 2710511..2711446 - 936 WP_058517920.1 DNA-3-methyladenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-259)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(9-56)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31902.98 Da        Isoelectric Point: 7.9767

>T272285 WP_062725383.1 NZ_CP117814:c2707569-2706718 [Legionella pneumophila]
MTKNIGESLRSRLKNIAVKEGSDFNAVLTRYGLERMLYRIGESEYSNQFLLKGALLFNLWYDMPHRPTKDIDLLGFGDND
MAYIKQTFSKICSISADDGISFLSESVTVNTIKKDGGYTGARVELFGELAKAKIKIQIDIGYGDAVTPRPIDAHYPVLLS
DLPAPKIRTYPIYTVIAEKLHAIAFLGMANSRLKDYLDLYVLLNNEQLDNQILAKAIQATFNRRGMTLPEALPIGLTDEF
ANDPTRESMWKAFLRKNELEQKSLTEVIVVIRNLILMPFALAK

Download         Length: 852 bp

Antitoxin


Download         Length: 203 a.a.        Molecular weight: 22947.90 Da        Isoelectric Point: 9.7451

>AT272285 WP_062725381.1 NZ_CP117814:c2708174-2707566 [Legionella pneumophila]
MKTEATYKQKVLQMASKTGIVRMSDLTKRGITRATISRLVSENKLEKLASGLYCLPETEFSEKESLIIIASRVPKAVFCL
LTALQIHELTTQLPRKVWIAMPKGSHTPKMDYPPVKMVQYSDEAFSEGIEIIDSDNIKLRVYNLAKTIADSFKHRNKIGL
DVAIEALKEAYSKNKVTVDELWHYAKICRVANVMRPYIEAIQ

Download         Length: 609 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References