Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2338952..2339736 Replicon chromosome
Accession NZ_CP117812
Organism Lentisphaera profundi strain SAORIC-696

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag PQO03_RS20620 Protein ID WP_274153068.1
Coordinates 2339326..2339736 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag PQO03_RS20615 Protein ID WP_274153066.1
Coordinates 2338952..2339329 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQO03_RS20590 (PQO03_20590) 2334088..2335041 + 954 WP_274153060.1 SDR family oxidoreductase -
PQO03_RS20595 (PQO03_20595) 2335193..2335516 + 324 Protein_1770 four helix bundle protein -
PQO03_RS20600 (PQO03_20600) 2335914..2337287 + 1374 WP_274153061.1 nucleotide sugar dehydrogenase -
PQO03_RS20605 (PQO03_20605) 2337450..2337797 + 348 WP_274153062.1 four helix bundle protein -
PQO03_RS20610 (PQO03_20610) 2337890..2338651 + 762 WP_274153064.1 glycosyltransferase family 2 protein -
PQO03_RS20615 (PQO03_20615) 2338952..2339329 + 378 WP_274153066.1 nucleotidyltransferase domain-containing protein Antitoxin
PQO03_RS20620 (PQO03_20620) 2339326..2339736 + 411 WP_274153068.1 DUF86 domain-containing protein Toxin
PQO03_RS20625 (PQO03_20625) 2340197..2342593 - 2397 WP_274153070.1 N,N'-diacetylchitobiose phosphorylase -
PQO03_RS20630 (PQO03_20630) 2343176..2344444 + 1269 WP_274153072.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-132)

Antitoxin

Polymerase beta, nucleotidyltransferase

(7-92)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15597.90 Da        Isoelectric Point: 5.6039

>T272283 WP_274153068.1 NZ_CP117812:2339326-2339736 [Lentisphaera profundi]
MIDDVKFNKLNTIERCLKRIDEEYQNSHERYLSSFTIQDSIILNLQRACEASIDLAMHLIAQGKLGIPQTSRDAFKILEE
KQMIDSNLSKELQAMVGFRNIAVHDYQDLQGPIVLAILDKHLSSFTDFIQKINSLS

Download         Length: 411 bp

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14138.97 Da        Isoelectric Point: 5.1028

>AT272283 WP_274153066.1 NZ_CP117812:2338952-2339329 [Lentisphaera profundi]
MITINTEHIIKSLQELHPEGLILFGSHSKGCARKDSDIDIAFLSSKSFSEYDVFCKAEALASELNCDINLINLQNASTVF
AYNILTSGTILQISNDYHWNRFSYLTYSLYAKLNEERHEILTAVS

Download         Length: 378 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References