Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1673092..1673620 Replicon chromosome
Accession NZ_CP117812
Organism Lentisphaera profundi strain SAORIC-696

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PQO03_RS17865 Protein ID WP_274152244.1
Coordinates 1673092..1673379 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PQO03_RS17870 Protein ID WP_274152246.1
Coordinates 1673369..1673620 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQO03_RS17855 (PQO03_17855) 1668188..1669600 - 1413 WP_274152241.1 DUF1501 domain-containing protein -
PQO03_RS17860 (PQO03_17860) 1669590..1672757 - 3168 WP_274152242.1 PSD1 and planctomycete cytochrome C domain-containing protein -
PQO03_RS17865 (PQO03_17865) 1673092..1673379 - 288 WP_274152244.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PQO03_RS17870 (PQO03_17870) 1673369..1673620 - 252 WP_274152246.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PQO03_RS17875 (PQO03_17875) 1673923..1675143 - 1221 WP_274152247.1 aldose 1-epimerase family protein -
PQO03_RS17880 (PQO03_17880) 1675159..1676010 - 852 WP_274152249.1 shikimate dehydrogenase -
PQO03_RS17885 (PQO03_17885) 1676022..1677302 - 1281 WP_274152251.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-76)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11348.25 Da        Isoelectric Point: 10.5941

>T272282 WP_274152244.1 NZ_CP117812:c1673379-1673092 [Lentisphaera profundi]
MSYDLSFLPSAKKEWDKLGHTIKEQFKKKLEKVLNEPRIEQNKLSGHSNLYKIKLRSSGYRLAYEVINNEMIIYVISVGK
RENNSIYKRMNRRLK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9395.67 Da        Isoelectric Point: 4.4131

>AT272282 WP_274152246.1 NZ_CP117812:c1673620-1673369 [Lentisphaera profundi]
MQSLLSDYSASISELKKNPTALLNESEGSPIVILNHNTPTAYLISADSYENMMNYIEDLELIQIHKERIKEKSQAIKVTL
DEL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References