Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2787167..2787669 Replicon chromosome
Accession NZ_CP117811
Organism Lentisphaera profundi strain SAORIC-696

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PQO03_RS11455 Protein ID WP_274150397.1
Coordinates 2787167..2787421 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PQO03_RS11460 Protein ID WP_274150398.1
Coordinates 2787418..2787669 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQO03_RS11425 (PQO03_11425) 2782712..2783086 - 375 WP_274150392.1 hypothetical protein -
PQO03_RS11430 (PQO03_11430) 2783410..2783706 - 297 WP_274150393.1 type II toxin-antitoxin system RelE/ParE family toxin -
PQO03_RS11435 (PQO03_11435) 2783703..2783906 - 204 WP_274150394.1 addiction module protein -
PQO03_RS11440 (PQO03_11440) 2784317..2784691 - 375 WP_274150395.1 hypothetical protein -
PQO03_RS11445 (PQO03_11445) 2784833..2785357 - 525 WP_274150396.1 hypothetical protein -
PQO03_RS11450 (PQO03_11450) 2785841..2787010 - 1170 WP_274149230.1 transposase -
PQO03_RS11455 (PQO03_11455) 2787167..2787421 - 255 WP_274150397.1 Txe/YoeB family addiction module toxin Toxin
PQO03_RS11460 (PQO03_11460) 2787418..2787669 - 252 WP_274150398.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PQO03_RS11465 (PQO03_11465) 2787820..2788191 - 372 WP_274150399.1 hypothetical protein -
PQO03_RS11470 (PQO03_11470) 2788943..2789302 - 360 WP_274150400.1 hypothetical protein -
PQO03_RS11475 (PQO03_11475) 2790270..2790530 - 261 WP_274150401.1 hypothetical protein -
PQO03_RS11480 (PQO03_11480) 2790909..2791247 - 339 WP_274150402.1 hypothetical protein -
PQO03_RS11485 (PQO03_11485) 2791306..2791704 - 399 WP_274150403.1 phosphopantetheine-binding protein -
PQO03_RS11490 (PQO03_11490) 2791751..2792461 - 711 WP_274150404.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2777256..2801182 23926
- inside Integron - fcl 227..2808340 2808113
- inside Integron - - 2779738..2789640 9902


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10170.82 Da        Isoelectric Point: 10.1005

>T272281 WP_274150397.1 NZ_CP117811:c2787421-2787167 [Lentisphaera profundi]
MKITFSTKAWEDYLYWQKQDKKILKRINLLIKDIERNPNDGLGKPEILRNTLSGYCSRRITDEHRLVYKILDNNLILIQA
RHHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9498.77 Da        Isoelectric Point: 4.6386

>AT272281 WP_274150398.1 NZ_CP117811:c2787669-2787418 [Lentisphaera profundi]
MNAMTYTEARQNLAKTMETVCNNHDPVIITSKRERSVVMISLEDYSAMEETSYLLRSPKNAKRLLESIYEIENGGGVERD
LIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References