Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2481928..2482465 Replicon chromosome
Accession NZ_CP117797
Organism Fusobacterium nucleatum strain FNA

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PSR68_RS11830 Protein ID WP_273904344.1
Coordinates 2481928..2482200 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PSR68_RS11835 Protein ID WP_273904345.1
Coordinates 2482202..2482465 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR68_RS11810 (PSR68_11810) 2478654..2479901 - 1248 WP_273904342.1 Fic family protein -
PSR68_RS11815 (PSR68_11815) 2479997..2480551 + 555 WP_273904343.1 DUF1877 family protein -
PSR68_RS11820 (PSR68_11820) 2480548..2481237 - 690 WP_005910338.1 DUF554 domain-containing protein -
PSR68_RS11825 (PSR68_11825) 2481390..2481886 + 497 Protein_2300 AAA family ATPase -
PSR68_RS11830 (PSR68_11830) 2481928..2482200 - 273 WP_273904344.1 type II toxin-antitoxin system YafQ family toxin Toxin
PSR68_RS11835 (PSR68_11835) 2482202..2482465 - 264 WP_273904345.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PSR68_RS11840 (PSR68_11840) 2482541..2483047 - 507 WP_273904347.1 transcription repressor NadR -
PSR68_RS11845 (PSR68_11845) 2483040..2483900 - 861 WP_273904348.1 carboxylating nicotinate-nucleotide diphosphorylase -
PSR68_RS11850 (PSR68_11850) 2483878..2485170 - 1293 WP_273904349.1 L-aspartate oxidase -
PSR68_RS11855 (PSR68_11855) 2485172..2486068 - 897 WP_273904350.1 quinolinate synthase NadA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10671.46 Da        Isoelectric Point: 8.7819

>T272271 WP_273904344.1 NZ_CP117797:c2482200-2481928 [Fusobacterium nucleatum]
MYEIKTTTKFEKDLKLMKKRGYDLKLLKEVIDILSNGEELSSKYKDHYLQGDYIGFKECHIKPDWLLVYKIDNNILVLTL
SRTGKHSDLF

Download         Length: 273 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9884.46 Da        Isoelectric Point: 5.1743

>AT272271 WP_273904345.1 NZ_CP117797:c2482465-2482202 [Fusobacterium nucleatum]
MAVINIRVNDEVKKEAESIFKSLGLNMSVAMNLFLKKCINENGIPFDLKIPNRETIEALEETNKILNGNIKRKSYKNADE
LFEDLGV

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References