Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 65682..66189 Replicon chromosome
Accession NZ_CP117797
Organism Fusobacterium nucleatum strain FNA

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PSR68_RS00380 Protein ID WP_273905737.1
Coordinates 65929..66189 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag PSR68_RS00375 Protein ID WP_100028241.1
Coordinates 65682..65936 (+) Length 85 a.a.

Genomic Context

PSR68_RS00360PSR68_RS00365PSR68_RS00370PSR68_RS00375PSR68_RS00380PSR68_RS00385PSR68_RS00390PSR68_RS00395PSR68_RS00400PSR68_RS00405
Location: 62276..62644 (369 bp)
Type: Others
Protein ID: WP_273904451.1
Location: 62645..63919 (1275 bp)
Type: Others
Protein ID: WP_273904453.1
Location: 64180..65388 (1209 bp)
Type: Others
Protein ID: WP_273904455.1
Location: 65682..65936 (255 bp)
Type: Antitoxin
Protein ID: WP_100028241.1
Location: 65929..66189 (261 bp)
Type: Toxin
Protein ID: WP_273905737.1
Location: 66206..66694 (489 bp)
Type: Others
Protein ID: WP_273905738.1
Location: 66931..67581 (651 bp)
Type: Others
Protein ID: WP_273904460.1
Location: 67659..68852 (1194 bp)
Type: Others
Protein ID: WP_005910264.1
Location: 68908..69303 (396 bp)
Type: Others
Protein ID: WP_005910263.1
Location: 69388..70644 (1257 bp)
Type: Others
Protein ID: WP_008796201.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PSR68_RS00360 (PSR68_00360)62276..62644+369WP_273904451.1arsenate reductase family protein-
PSR68_RS00365 (PSR68_00365)62645..63919+1275WP_273904453.1branched-chain amino acid transport system II carrier protein-
PSR68_RS00370 (PSR68_00370)64180..65388+1209WP_273904455.1tyrosine--tRNA ligase-
PSR68_RS00375 (PSR68_00375)65682..65936+255WP_100028241.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
PSR68_RS00380 (PSR68_00380)65929..66189+261WP_273905737.1Txe/YoeB family addiction module toxinToxin
PSR68_RS00385 (PSR68_00385)66206..66694+489WP_273905738.1GNAT family protein-
PSR68_RS00390 (PSR68_00390)66931..67581+651WP_273904460.1endonuclease III-
PSR68_RS00395 (PSR68_00395)67659..68852+1194WP_005910264.1cysteine desulfurase NifS-
PSR68_RS00400 (PSR68_00400)68908..69303+396WP_005910263.1Fe-S cluster assembly scaffold protein NifU-
PSR68_RS00405 (PSR68_00405)69388..70644+1257WP_008796201.1serine hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10264.85 Da        Isoelectric Point: 10.0493

>T272269 WP_273905737.1 NZ_CP117797:65929-66189 [Fusobacterium nucleatum]
MNNLVWTHKAWQDYLYWQTQDKKTLKKINKLVKGIERNGALNGIGKPEVLKNENAYSRRIDEKNRLVYRIVDGFIWIIAC
KGHYEE

Download         Length: 261 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9796.12 Da        Isoelectric Point: 4.4453

>AT272269 WP_100028241.1 NZ_CP117797:65682-65936 [Fusobacterium nucleatum]
MLAINYTTLRTNLKSYFDKAVDNDEDIIITRKNERNVVLLSLDKYNEFLKAMRNLEYMTKIREGIAELEAGKGEIHDLIE
ADDE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References