Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 65682..66189 Replicon chromosome
Accession NZ_CP117797
Organism Fusobacterium nucleatum strain FNA

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PSR68_RS00380 Protein ID WP_273905737.1
Coordinates 65929..66189 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag PSR68_RS00375 Protein ID WP_100028241.1
Coordinates 65682..65936 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSR68_RS00360 (PSR68_00360) 62276..62644 + 369 WP_273904451.1 arsenate reductase family protein -
PSR68_RS00365 (PSR68_00365) 62645..63919 + 1275 WP_273904453.1 branched-chain amino acid transport system II carrier protein -
PSR68_RS00370 (PSR68_00370) 64180..65388 + 1209 WP_273904455.1 tyrosine--tRNA ligase -
PSR68_RS00375 (PSR68_00375) 65682..65936 + 255 WP_100028241.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PSR68_RS00380 (PSR68_00380) 65929..66189 + 261 WP_273905737.1 Txe/YoeB family addiction module toxin Toxin
PSR68_RS00385 (PSR68_00385) 66206..66694 + 489 WP_273905738.1 GNAT family protein -
PSR68_RS00390 (PSR68_00390) 66931..67581 + 651 WP_273904460.1 endonuclease III -
PSR68_RS00395 (PSR68_00395) 67659..68852 + 1194 WP_005910264.1 cysteine desulfurase NifS -
PSR68_RS00400 (PSR68_00400) 68908..69303 + 396 WP_005910263.1 Fe-S cluster assembly scaffold protein NifU -
PSR68_RS00405 (PSR68_00405) 69388..70644 + 1257 WP_008796201.1 serine hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10264.85 Da        Isoelectric Point: 10.0493

>T272269 WP_273905737.1 NZ_CP117797:65929-66189 [Fusobacterium nucleatum]
MNNLVWTHKAWQDYLYWQTQDKKTLKKINKLVKGIERNGALNGIGKPEVLKNENAYSRRIDEKNRLVYRIVDGFIWIIAC
KGHYEE

Download         Length: 261 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9796.12 Da        Isoelectric Point: 4.4453

>AT272269 WP_100028241.1 NZ_CP117797:65682-65936 [Fusobacterium nucleatum]
MLAINYTTLRTNLKSYFDKAVDNDEDIIITRKNERNVVLLSLDKYNEFLKAMRNLEYMTKIREGIAELEAGKGEIHDLIE
ADDE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References