Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 742650..743889 Replicon chromosome
Accession NZ_CP117781
Organism Burkholderia sp. FERM BP-3421

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Bsp3421_RS06410 Protein ID WP_273997506.1
Coordinates 742650..743240 (-) Length 197 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag Bsp3421_RS06415 Protein ID WP_273997507.1
Coordinates 743284..743889 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Bsp3421_RS06385 (Bsp3421_001276) 738258..739055 + 798 WP_273997501.1 hypothetical protein -
Bsp3421_RS06390 (Bsp3421_001277) 739055..739423 + 369 WP_273997502.1 hypothetical protein -
Bsp3421_RS06395 (Bsp3421_001278) 739443..740879 + 1437 WP_273997503.1 Do family serine endopeptidase -
Bsp3421_RS06400 (Bsp3421_001279) 740892..741284 - 393 WP_273997504.1 carboxymuconolactone decarboxylase family protein -
Bsp3421_RS06405 (Bsp3421_001280) 741476..742450 - 975 WP_273997505.1 helix-turn-helix domain-containing protein -
Bsp3421_RS06410 (Bsp3421_001281) 742650..743240 - 591 WP_273997506.1 HD domain-containing protein Toxin
Bsp3421_RS06415 (Bsp3421_001282) 743284..743889 - 606 WP_273997507.1 helix-turn-helix transcriptional regulator Antitoxin
Bsp3421_RS06420 (Bsp3421_001283) 744027..744398 - 372 WP_273997508.1 hypothetical protein -
Bsp3421_RS06425 (Bsp3421_001284) 744507..744755 - 249 WP_273997509.1 hypothetical protein -
Bsp3421_RS06430 (Bsp3421_001285) 745180..746490 + 1311 WP_273997510.1 leucine-rich repeat-containing protein kinase family protein -
Bsp3421_RS06435 (Bsp3421_001286) 746518..747090 - 573 WP_273997511.1 hypothetical protein -
Bsp3421_RS06440 (Bsp3421_001287) 747286..748050 + 765 WP_273997512.1 metallophosphoesterase -
Bsp3421_RS06445 (Bsp3421_001288) 748132..748266 + 135 Protein_632 IS5/IS1182 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 197 a.a.        Molecular weight: 21877.58 Da        Isoelectric Point: 5.3206

>T272264 WP_273997506.1 NZ_CP117781:c743240-742650 [Burkholderia sp. FERM BP-3421]
MDLDTLKGRLAFLREAERLKDVLRSGHTSSGRPESTAEHSWRLCLMALVFSDALDGVDPLRMLGMCVVHDLGEAIHGDIP
ATEQHAHPDKSARERQDLLHLSRALDDGMRARLLALWDDYERAASPEARAVKAFDKLETILQHAQGKNPDDFDYAFNLAY
GRRYTSAAPLFEALRALVDADTQARIDTRPDAQAEA

Download         Length: 591 bp

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 21994.31 Da        Isoelectric Point: 9.5456

>AT272264 WP_273997507.1 NZ_CP117781:c743889-743284 [Burkholderia sp. FERM BP-3421]
MHDTRLHPVPIGAAFKRWRRLHRIKQAHAAALFGVAQSTISRWESGLHDMEPAERARVEHVLSARLDAPADHALARLVRE
SPRPVHLVCDLTHRLLACSPTRAAEFGAPLADLLGRSLWRYATPEIMGQEAALDTLGWRDSLAPPALEFATGVNGSAIVP
IHAGRCRWTRMTLADGTSARLVETLRPAAHISCVDAARGIP

Download         Length: 606 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References