Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 141025..141575 Replicon plasmid p2
Accession NZ_CP117779
Organism Burkholderia sp. FERM BP-3421

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag Bsp3421_RS00650 Protein ID WP_273994925.1
Coordinates 141285..141575 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Bsp3421_RS00645 Protein ID WP_273994924.1
Coordinates 141025..141297 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Bsp3421_RS00625 (Bsp3421_000125) 136096..137088 + 993 WP_273994920.1 ATP-binding protein -
Bsp3421_RS00630 (Bsp3421_000126) 137085..138554 + 1470 WP_273994921.1 hypothetical protein -
Bsp3421_RS00635 (Bsp3421_000127) 138731..139363 + 633 WP_273994922.1 hypothetical protein -
Bsp3421_RS00640 (Bsp3421_000128) 139523..140269 + 747 WP_273994923.1 hypothetical protein -
Bsp3421_RS00645 (Bsp3421_000129) 141025..141297 + 273 WP_273994924.1 ribbon-helix-helix protein, CopG family Antitoxin
Bsp3421_RS00650 (Bsp3421_000130) 141285..141575 + 291 WP_273994925.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Bsp3421_RS00655 (Bsp3421_000131) 141620..141805 + 186 WP_273994927.1 hypothetical protein -
Bsp3421_RS00660 (Bsp3421_000132) 141811..142053 + 243 WP_273994928.1 hypothetical protein -
Bsp3421_RS00665 (Bsp3421_000133) 142246..142884 + 639 WP_273994929.1 helix-turn-helix domain-containing protein -
Bsp3421_RS00670 (Bsp3421_000134) 142912..143190 + 279 WP_273994930.1 hypothetical protein -
Bsp3421_RS00675 (Bsp3421_000135) 143261..143464 + 204 WP_273994932.1 hypothetical protein -
Bsp3421_RS00680 (Bsp3421_000136) 143519..144307 + 789 WP_273994934.1 hypothetical protein -
Bsp3421_RS00685 (Bsp3421_000137) 144304..144597 + 294 WP_273994935.1 hypothetical protein -
Bsp3421_RS00690 (Bsp3421_000138) 144594..145004 + 411 WP_273994936.1 hypothetical protein -
Bsp3421_RS00695 (Bsp3421_000139) 145010..145384 + 375 WP_273994937.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..238570 238570


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10916.53 Da        Isoelectric Point: 7.2020

>T272263 WP_273994925.1 NZ_CP117779:141285-141575 [Burkholderia sp. FERM BP-3421]
VPQVIWTRNAARAVQRMHQFLAMKDPTAAQRAVKAIRAGVDVLIDQPRLGRPVDDLDVEFREWLIDFGDSGYVVLYRVDE
AGVVILTVRHQREAGY

Download         Length: 291 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10660.00 Da        Isoelectric Point: 6.6424

>AT272263 WP_273994924.1 NZ_CP117779:141025-141297 [Burkholderia sp. FERM BP-3421]
MATSIKLDTGMQDRVRHLAEQRRRTPHWIMREAIAQYVEREEKRESIRQEAVEAWHDYQTTGLHVPHADMDRYMAELEAG
RDAELPGCRK

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References