Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2186064..2186717 Replicon chromosome
Accession NZ_CP117764
Organism Acinetobacter baumannii strain 2022CK-00784

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PTC86_RS10295 Protein ID WP_000607077.1
Coordinates 2186064..2186453 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PTC86_RS10300 Protein ID WP_001288210.1
Coordinates 2186460..2186717 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC86_RS10280 (PTC86_10280) 2181182..2183377 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
PTC86_RS10285 (PTC86_10285) 2183565..2184131 - 567 WP_000651538.1 rhombosortase -
PTC86_RS10290 (PTC86_10290) 2184209..2185294 - 1086 WP_000049106.1 hypothetical protein -
PTC86_RS10295 (PTC86_10295) 2186064..2186453 - 390 WP_000607077.1 membrane protein Toxin
PTC86_RS10300 (PTC86_10300) 2186460..2186717 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PTC86_RS10305 (PTC86_10305) 2186905..2188077 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
PTC86_RS10310 (PTC86_10310) 2188126..2189616 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
PTC86_RS10315 (PTC86_10315) 2189798..2190175 - 378 WP_001216380.1 50S ribosomal protein L17 -
PTC86_RS10320 (PTC86_10320) 2190194..2191201 - 1008 WP_273780449.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T272260 WP_000607077.1 NZ_CP117764:c2186453-2186064 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT272260 WP_001288210.1 NZ_CP117764:c2186717-2186460 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References