Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3313151..3313804 Replicon chromosome
Accession NZ_CP117762
Organism Acinetobacter baumannii strain 2022CK-00839

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PTC93_RS16000 Protein ID WP_000607077.1
Coordinates 3313151..3313540 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PTC93_RS16005 Protein ID WP_001288210.1
Coordinates 3313547..3313804 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC93_RS15985 (PTC93_15975) 3308269..3310464 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
PTC93_RS15990 (PTC93_15980) 3310652..3311218 - 567 WP_000651538.1 rhombosortase -
PTC93_RS15995 (PTC93_15985) 3311296..3312381 - 1086 WP_000049106.1 hypothetical protein -
PTC93_RS16000 (PTC93_15990) 3313151..3313540 - 390 WP_000607077.1 membrane protein Toxin
PTC93_RS16005 (PTC93_15995) 3313547..3313804 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PTC93_RS16010 (PTC93_16000) 3313992..3315164 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
PTC93_RS16015 (PTC93_16005) 3315213..3316703 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
PTC93_RS16020 (PTC93_16010) 3316885..3317262 - 378 WP_001216380.1 50S ribosomal protein L17 -
PTC93_RS16025 (PTC93_16015) 3317281..3318288 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T272258 WP_000607077.1 NZ_CP117762:c3313540-3313151 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT272258 WP_001288210.1 NZ_CP117762:c3313804-3313547 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References