Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 463141..463794 Replicon chromosome
Accession NZ_CP117759
Organism Acinetobacter baumannii strain 2022CK-00843

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PTC92_RS02255 Protein ID WP_000607077.1
Coordinates 463405..463794 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PTC92_RS02250 Protein ID WP_001288210.1
Coordinates 463141..463398 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC92_RS02230 (PTC92_02230) 458657..459664 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
PTC92_RS02235 (PTC92_02235) 459683..460060 + 378 WP_001216380.1 50S ribosomal protein L17 -
PTC92_RS02240 (PTC92_02240) 460242..461732 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
PTC92_RS02245 (PTC92_02245) 461781..462953 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
PTC92_RS02250 (PTC92_02250) 463141..463398 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PTC92_RS02255 (PTC92_02255) 463405..463794 + 390 WP_000607077.1 membrane protein Toxin
PTC92_RS02260 (PTC92_02260) 464564..465649 + 1086 WP_000049106.1 hypothetical protein -
PTC92_RS02265 (PTC92_02265) 465727..466293 + 567 WP_000651538.1 rhombosortase -
PTC92_RS02270 (PTC92_02270) 466481..468676 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T272256 WP_000607077.1 NZ_CP117759:463405-463794 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT272256 WP_001288210.1 NZ_CP117759:463141-463398 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References