Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008742..2008951 Replicon chromosome
Accession NZ_CP117750
Organism Enterobacter hormaechei strain 2022CK-00700

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008755..2008858 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008742..2008951 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC84_RS09800 (PTC84_09800) 2005010..2006458 + 1449 WP_195207010.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PTC84_RS09805 (PTC84_09805) 2006565..2006804 + 240 WP_003859885.1 YebV family protein -
PTC84_RS09810 (PTC84_09810) 2006839..2007483 - 645 WP_015570293.1 protein-serine/threonine phosphatase -
PTC84_RS09815 (PTC84_09815) 2007651..2008631 + 981 WP_062938806.1 VirK/YbjX family protein -
PTC84_RS09820 (PTC84_09820) 2008677..2008874 + 198 WP_017693250.1 hypothetical protein -
- 2008742..2008951 + 210 - - Antitoxin
- 2008755..2008858 - 104 - - Toxin
PTC84_RS09825 (PTC84_09825) 2009000..2009338 - 339 WP_003859787.1 YebY family protein -
PTC84_RS09830 (PTC84_09830) 2009355..2010224 - 870 WP_017693249.1 copper homeostasis membrane protein CopD -
PTC84_RS09835 (PTC84_09835) 2010226..2010597 - 372 WP_017384342.1 CopC domain-containing protein YobA -
PTC84_RS09840 (PTC84_09840) 2010735..2010965 + 231 WP_003859784.1 DNA polymerase III subunit theta -
PTC84_RS09845 (PTC84_09845) 2011077..2011727 + 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
PTC84_RS09850 (PTC84_09850) 2011752..2012414 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1999640..2074254 74614
- inside Prophage - - 1992097..2074254 82157


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T272242 NZ_CP117750:c2008858-2008755 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 210 bp

>AT272242 NZ_CP117750:2008742-2008951 [Enterobacter hormaechei]
TTTTCAAGCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTA
AAAGTGGTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References