Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
Location | 1895245..1896753 | Replicon | chromosome |
Accession | NZ_CP117749 | ||
Organism | Pseudomonas aeruginosa strain 2022CK-00828 |
Toxin (Protein)
Gene name | - | Uniprot ID | Q9HYX1 |
Locus tag | PTC91_RS08900 | Protein ID | WP_003119682.1 |
Coordinates | 1895245..1895832 (+) | Length | 196 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | PTC91_RS08905 | Protein ID | WP_019484607.1 |
Coordinates | 1895899..1896753 (+) | Length | 285 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PTC91_RS08895 (PTC91_08895) | 1891500..1894979 | - | 3480 | WP_003091610.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
PTC91_RS08900 (PTC91_08900) | 1895245..1895832 | + | 588 | WP_003119682.1 | GNAT family protein | Toxin |
PTC91_RS08905 (PTC91_08905) | 1895899..1896753 | + | 855 | WP_019484607.1 | AraC family transcriptional regulator | Antitoxin |
PTC91_RS08910 (PTC91_08910) | 1896850..1899015 | + | 2166 | WP_019484608.1 | TonB-dependent receptor family protein | - |
PTC91_RS08915 (PTC91_08915) | 1899190..1901064 | + | 1875 | WP_003117607.1 | MFS transporter | - |
PTC91_RS08920 (PTC91_08920) | 1901125..1901334 | - | 210 | WP_003091604.1 | cold-shock protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 196 a.a. Molecular weight: 21901.23 Da Isoelectric Point: 9.8676
>T272231 WP_003119682.1 NZ_CP117749:1895245-1895832 [Pseudomonas aeruginosa]
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
MSRRAPMFKPLPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGRALPLAVRLGVQLV
GTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRN
HRRLAGGRLDDTFVYSITDHEWPQVKAALEASFTG
Download Length: 588 bp
Antitoxin
Download Length: 285 a.a. Molecular weight: 31909.24 Da Isoelectric Point: 7.5295
>AT272231 WP_019484607.1 NZ_CP117749:1895899-1896753 [Pseudomonas aeruginosa]
VPDEMSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPPGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETMLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE
VPDEMSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPPGSMVLINPDEVHTGSK
AHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHAGSLETQTRWRETMLALFRRH
ARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRA
PLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTTYE
Download Length: 855 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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