Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2024160..2024305 | Replicon | chromosome |
| Accession | NZ_CP117745 | ||
| Organism | Klebsiella pneumoniae strain 2022CK-00752 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2024196..2024298 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2024160..2024305 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PTC85_RS09850 | 2019290..2021350 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| PTC85_RS09855 | 2021354..2022013 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| PTC85_RS09860 | 2022092..2022322 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| PTC85_RS09865 | 2022435..2022809 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| PTC85_RS09870 | 2022813..2023682 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| PTC85_RS09875 | 2023699..2024037 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2024160..2024305 | - | 146 | - | - | Antitoxin |
| - | 2024196..2024298 | + | 103 | - | - | Toxin |
| PTC85_RS09880 | 2024674..2024817 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| PTC85_RS09885 | 2024922..2025890 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| PTC85_RS09890 | 2026047..2026700 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| PTC85_RS09895 | 2026697..2026888 | - | 192 | WP_002911395.1 | YebW family protein | - |
| PTC85_RS09900 | 2026986..2027225 | - | 240 | WP_002911393.1 | YebV family protein | - |
| PTC85_RS09905 | 2027341..2028774 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T272217 NZ_CP117745:2024196-2024298 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT272217 NZ_CP117745:c2024305-2024160 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
