Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2018696..2018841 | Replicon | chromosome |
| Accession | NZ_CP117740 | ||
| Organism | Klebsiella pneumoniae strain 2022CK-00768 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2018732..2018834 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2018696..2018841 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PTC88_RS09820 | 2013826..2015886 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| PTC88_RS09825 | 2015890..2016549 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| PTC88_RS09830 | 2016628..2016858 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| PTC88_RS09835 | 2016971..2017345 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| PTC88_RS09840 | 2017349..2018218 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| PTC88_RS09845 | 2018235..2018573 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2018696..2018841 | - | 146 | - | - | Antitoxin |
| - | 2018732..2018834 | + | 103 | - | - | Toxin |
| PTC88_RS09850 | 2019210..2019353 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| PTC88_RS09855 | 2019458..2020426 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| PTC88_RS09860 | 2020583..2021236 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| PTC88_RS09865 | 2021233..2021424 | - | 192 | WP_002911395.1 | YebW family protein | - |
| PTC88_RS09870 | 2021522..2021761 | - | 240 | WP_002911393.1 | YebV family protein | - |
| PTC88_RS09875 | 2021877..2023310 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T272199 NZ_CP117740:2018732-2018834 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT272199 NZ_CP117740:c2018841-2018696 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
