Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3485573..3485741 Replicon chromosome
Accession NZ_CP117730
Organism Klebsiella grimontii strain 2022CK-00781

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3485580..3485683 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3485573..3485741 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC90_RS16460 (PTC90_16455) 3480847..3481365 + 519 WP_154926358.1 spore coat U domain-containing protein -
PTC90_RS16465 (PTC90_16460) 3481384..3482148 + 765 WP_148855291.1 fimbria/pilus periplasmic chaperone -
PTC90_RS16470 (PTC90_16465) 3482151..3484481 + 2331 WP_148855292.1 fimbria/pilus outer membrane usher protein -
PTC90_RS16475 (PTC90_16470) 3484496..3485455 + 960 WP_049085573.1 spore coat protein U domain-containing protein -
- 3485573..3485741 + 169 - - Antitoxin
- 3485580..3485683 - 104 - - Toxin
PTC90_RS16480 (PTC90_16475) 3485841..3486179 - 339 WP_004103344.1 YebY family protein -
PTC90_RS16485 (PTC90_16480) 3486196..3487065 - 870 WP_004134819.1 copper homeostasis membrane protein CopD -
PTC90_RS16490 (PTC90_16485) 3487070..3487444 - 375 WP_064411566.1 CopC domain-containing protein YobA -
PTC90_RS16495 (PTC90_16490) 3487580..3487810 + 231 WP_004103351.1 DNA polymerase III subunit theta -
PTC90_RS16500 (PTC90_16495) 3487889..3488548 + 660 WP_148855293.1 exodeoxyribonuclease X -
PTC90_RS16505 (PTC90_16500) 3488555..3490615 - 2061 WP_116943571.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T272184 NZ_CP117730:c3485683-3485580 [Klebsiella grimontii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT272184 NZ_CP117730:3485573-3485741 [Klebsiella grimontii]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References