Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 1047646..1048465 Replicon chromosome
Accession NZ_CP117730
Organism Klebsiella grimontii strain 2022CK-00781

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag PTC90_RS04895 Protein ID WP_004132607.1
Coordinates 1047646..1047903 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag PTC90_RS04900 Protein ID WP_004132606.1
Coordinates 1047914..1048465 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTC90_RS04880 (PTC90_04880) 1043413..1044189 - 777 WP_004129229.1 Uxu operon transcriptional regulator -
PTC90_RS04885 (PTC90_04885) 1044326..1045801 - 1476 WP_098363455.1 fructuronate reductase -
PTC90_RS04890 (PTC90_04890) 1045878..1047062 - 1185 WP_049085652.1 mannonate dehydratase -
PTC90_RS04895 (PTC90_04895) 1047646..1047903 + 258 WP_004132607.1 YjhX family toxin Toxin
PTC90_RS04900 (PTC90_04900) 1047914..1048465 + 552 WP_004132606.1 N-acetyltransferase Antitoxin
PTC90_RS04905 (PTC90_04905) 1048579..1048986 + 408 Protein_959 class I SAM-dependent methyltransferase -
PTC90_RS04910 (PTC90_04910) 1049365..1050111 + 747 WP_224238150.1 class I SAM-dependent methyltransferase -
PTC90_RS04915 (PTC90_04915) 1050214..1051554 - 1341 WP_154925062.1 carbohydrate porin -
PTC90_RS04920 (PTC90_04920) 1051678..1053075 - 1398 WP_004132593.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T272182 WP_004132607.1 NZ_CP117730:1047646-1047903 [Klebsiella grimontii]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT272182 WP_004132606.1 NZ_CP117730:1047914-1048465 [Klebsiella grimontii]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References