Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2052932..2053203 Replicon chromosome
Accession NZ_CP117717
Organism Escherichia coli strain B1S11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2053062..2053165 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2052932..2053203 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTA69_RS09945 2049487..2050149 - 663 WP_000944256.1 exodeoxyribonuclease X -
PTA69_RS09950 2050173..2050829 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
PTA69_RS09955 2050931..2051161 - 231 WP_000916763.1 DNA polymerase III subunit theta -
PTA69_RS09960 2051300..2051674 + 375 WP_000204699.1 CopC domain-containing protein YobA -
PTA69_RS09965 2051678..2052550 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
PTA69_RS09970 2052563..2052904 + 342 WP_000976472.1 YebY family protein -
- 2052932..2053203 - 272 - - Antitoxin
- 2053062..2053165 + 104 - - Toxin
PTA69_RS09975 2053300..2053956 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
PTA69_RS09980 2053957..2054148 - 192 WP_001296140.1 YebW family protein -
PTA69_RS09985 2054253..2054489 - 237 WP_001295499.1 YebV family protein -
PTA69_RS09990 2054607..2056046 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T272112 NZ_CP117717:2053062-2053165 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT272112 NZ_CP117717:c2053203-2052932 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References