Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 5344799..5345324 Replicon chromosome
Accession NZ_CP117709
Organism Streptomyces sp. MMBL 11-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PSQ21_RS23975 Protein ID WP_274032866.1
Coordinates 5344799..5345062 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PSQ21_RS23980 Protein ID WP_274032867.1
Coordinates 5345055..5345324 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSQ21_RS23950 5339885..5340640 + 756 WP_274032856.1 ROK family protein -
PSQ21_RS23955 5340754..5341413 - 660 WP_274032858.1 hypothetical protein -
PSQ21_RS23960 5341704..5342792 + 1089 WP_274032860.1 redox-regulated ATPase YchF -
PSQ21_RS23965 5343319..5343570 + 252 WP_148020499.1 type II toxin-antitoxin system VapB family antitoxin -
PSQ21_RS23970 5343567..5343983 + 417 WP_274032864.1 PIN domain nuclease -
PSQ21_RS23975 5344799..5345062 - 264 WP_274032866.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSQ21_RS23980 5345055..5345324 - 270 WP_274032867.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PSQ21_RS23985 5345705..5347450 + 1746 WP_274032870.1 class I SAM-dependent DNA methyltransferase -
PSQ21_RS23990 5347447..5348682 + 1236 WP_274032871.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-56)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10057.47 Da        Isoelectric Point: 7.2015

>T272076 WP_274032866.1 NZ_CP117709:c5345062-5344799 [Streptomyces sp. MMBL 11-1]
VSEYRTVFRPEAQAELRKVPRDMALRILAKLTELESDPLGFNTTALVSQPDRRRLRVGDYRVIYTIDDGELVVWVVHVGH
RSTVYDT

Download         Length: 264 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10250.70 Da        Isoelectric Point: 4.6168

>AT272076 WP_274032867.1 NZ_CP117709:c5345324-5345055 [Streptomyces sp. MMBL 11-1]
MTQPLPIESIRDVRAHLAEVVERADRDDVPTVITRRGKEVAAVVSIDVLRKYLEWEEREINRIIDERMANPASGIPIEDI
MRETLARSE

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References