272074

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2345810..2346374 Replicon chromosome
Accession NZ_CP117709
Organism Streptomyces sp. MMBL 11-1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PSQ21_RS10085 Protein ID WP_274030100.1
Coordinates 2345810..2346133 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PSQ21_RS10090 Protein ID WP_274030101.1
Coordinates 2346150..2346374 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSQ21_RS10075 2341121..2344423 + 3303 WP_274030099.1 S8 family serine peptidase -
PSQ21_RS10080 2344711..2345739 + 1029 WP_274035698.1 aspartate-semialdehyde dehydrogenase -
PSQ21_RS10085 2345810..2346133 - 324 WP_274030100.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PSQ21_RS10090 2346150..2346374 - 225 WP_274030101.1 ribbon-helix-helix domain-containing protein Antitoxin
PSQ21_RS10095 2346478..2349054 + 2577 WP_274030102.1 aminopeptidase N -
PSQ21_RS10100 2349268..2349801 + 534 WP_274030103.1 hypothetical protein -
PSQ21_RS10105 2349897..2351051 - 1155 WP_274030104.1 allantoicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-107)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-38)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11692.52 Da        Isoelectric Point: 11.3764

>T272074 WP_274030100.1 NZ_CP117709:c2346133-2345810 [Streptomyces sp. MMBL 11-1]
VDLEPARGSEANKVRPAVIVSNNAANRSVELTGRGVVAVVPLTSNTSRVLSFQVLLAAKESQLPQNSKVQCEQIRAVFPD
RVLKRIGEVPRQRMAEIDAALRRHLAL

Download         Length: 324 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8146.90 Da        Isoelectric Point: 3.8737

>AT272074 WP_274030101.1 NZ_CP117709:c2346374-2346150 [Streptomyces sp. MMBL 11-1]
MKISVSLPQEDVAFVDEYARKTDADSRSAVIHAAIELLRTAGLEAEYTEAFQEWDASEDAALWDRTVADGLTDA

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References