272061

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1955895..1956038 Replicon chromosome
Accession NZ_CP117698
Organism Salmonella enterica subsp. enterica serovar London strain L1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1955934..1956036 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1955895..1956038 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRJ38_RS09315 1952319..1953017 - 699 WP_023255939.1 exodeoxyribonuclease X -
PRJ38_RS09320 1953041..1953697 - 657 WP_023245437.1 carbon-nitrogen hydrolase family protein -
PRJ38_RS09325 1953805..1954035 - 231 WP_000856224.1 DNA polymerase III subunit theta -
PRJ38_RS09330 1954173..1954547 + 375 WP_000168393.1 CopC domain-containing protein YobA -
PRJ38_RS09335 1954548..1955423 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
PRJ38_RS09340 1955440..1955793 + 354 WP_000722368.1 YebY family protein -
- 1955895..1956038 - 144 - - Antitoxin
- 1955934..1956036 + 103 - - Toxin
PRJ38_RS09345 1956176..1957255 - 1080 WP_058107134.1 phage integrase Arm DNA-binding domain-containing protein -
PRJ38_RS09350 1957288..1958439 - 1152 Protein_1825 PD-(D/E)XK nuclease-like domain-containing protein -
PRJ38_RS09355 1958428..1958619 + 192 Protein_1826 glycoside hydrolase family 19 protein -
PRJ38_RS09360 1958673..1959206 + 534 WP_023256014.1 DUF2514 domain-containing protein -
PRJ38_RS09365 1959463..1959630 - 168 WP_000789530.1 lytic enzyme -
PRJ38_RS09370 1959695..1959883 - 189 WP_001034748.1 hypothetical protein -
PRJ38_RS09375 1959938..1960198 + 261 Protein_1830 DUF1441 family protein -
PRJ38_RS09380 1960200..1960415 + 216 Protein_1831 shikimate transporter -
PRJ38_RS09385 1960425..1960712 + 288 Protein_1832 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1932708..1976207 43499
- inside Prophage - sopE2 1932708..1989132 56424


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T272061 NZ_CP117698:1955934-1956036 [Salmonella enterica subsp. enterica serovar London]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT272061 NZ_CP117698:c1956038-1955895 [Salmonella enterica subsp. enterica serovar London]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References