Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 33627..34162 Replicon plasmid pEA11_1
Accession NZ_CP117669
Organism Escherichia albertii strain BIA_11

Toxin (Protein)


Gene name relE Uniprot ID A0A8H9KAX0
Locus tag PS054_RS23745 Protein ID WP_000222759.1
Coordinates 33875..34162 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8H9KB11
Locus tag PS054_RS23740 Protein ID WP_001132891.1
Coordinates 33627..33878 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS054_RS23725 (29522) 29522..29874 - 353 Protein_28 RepB family plasmid replication initiator protein -
PS054_RS23730 (30966) 30966..32132 + 1167 WP_054412873.1 plasmid-partitioning protein SopA -
PS054_RS23735 (32132) 32132..33103 + 972 WP_059276357.1 ParB/RepB/Spo0J family plasmid partition protein -
PS054_RS23740 (33627) 33627..33878 + 252 WP_001132891.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PS054_RS23745 (33875) 33875..34162 + 288 WP_000222759.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PS054_RS23750 (34298) 34298..35208 + 911 Protein_33 transposase -
PS054_RS23755 (35510) 35510..36223 - 714 WP_273815696.1 molecular chaperone -
PS054_RS23760 (36220) 36220..37548 - 1329 WP_273815697.1 fimbrial protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - vat 1..110945 110945


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11176.23 Da        Isoelectric Point: 10.5832

>T271974 WP_000222759.1 NZ_CP117669:33875-34162 [Escherichia albertii]
MTYTVKFRDDALKEWLKLDKSIQQQFAKKLKKCSENPHIPSAKLRELKNCYKIKLRASGFRLVYQVIDDMLIIAVVAVGK
RERSNVYNLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9181.39 Da        Isoelectric Point: 4.0780

>AT271974 WP_001132891.1 NZ_CP117669:33627-33878 [Escherichia albertii]
MPNIILSDTSASVSELKKNPMATVGAGDGYPVAILNRNQPAFYCVPAELYERMLDALDDQELVKLVTERSNQPLHDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References