Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1896818..1897555 Replicon chromosome
Accession NZ_CP117668
Organism Escherichia albertii strain BIA_11

Toxin (Protein)


Gene name yeeV Uniprot ID A0A8H9B962
Locus tag PS054_RS09640 Protein ID WP_038869372.1
Coordinates 1897175..1897555 (+) Length 127 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag PS054_RS09635 Protein ID WP_273815296.1
Coordinates 1896818..1897144 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS054_RS09605 (1892854) 1892854..1893729 + 876 WP_273815285.1 GTPase family protein -
PS054_RS09610 (1893942) 1893942..1894643 + 702 WP_273815286.1 WYL domain-containing protein -
PS054_RS09615 (1894649) 1894649..1895278 + 630 WP_273815288.1 hypothetical protein -
PS054_RS09620 (1895332) 1895332..1895775 + 444 WP_273815290.1 IrmA family protein -
PS054_RS09625 (1895906) 1895906..1896325 + 420 WP_273815292.1 antirestriction protein -
PS054_RS09630 (1896340) 1896340..1896807 + 468 WP_038869371.1 DNA repair protein RadC -
PS054_RS09635 (1896818) 1896818..1897144 + 327 WP_273815296.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PS054_RS09640 (1897175) 1897175..1897555 + 381 WP_038869372.1 TA system toxin CbtA family protein Toxin
PS054_RS09645 (1897724) 1897724..1897798 + 75 Protein_1891 hypothetical protein -
PS054_RS09650 (1898098) 1898098..1898160 + 63 Protein_1892 integrase -
PS054_RS09655 (1898775) 1898775..1898876 + 102 WP_000662203.1 small membrane protein YkgR -
PS054_RS09660 (1899335) 1899335..1899601 + 267 WP_000812362.1 type B 50S ribosomal protein L31 -
PS054_RS09665 (1899598) 1899598..1899738 + 141 WP_000866440.1 type B 50S ribosomal protein L36 -
PS054_RS09675 (1900845) 1900845..1902017 + 1173 Protein_1896 NADP-dependent succinate-semialdehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(5-103)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 14142.20 Da        Isoelectric Point: 7.9069

>T271960 WP_038869372.1 NZ_CP117668:1897175-1897555 [Escherichia albertii]
MQTLPLPEPRAARPCPSPVQVWQLLLTHLLNKHYGLTLNDTPFGDDRVIQAHINAGISLCDAVNFIVERYELVRIDHSRF
GLTERSSLIGAIDILRARRATGLIVSSGYSTITRITTGRYWEDTAQ

Download         Length: 381 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11996.71 Da        Isoelectric Point: 8.1541

>AT271960 WP_273815296.1 NZ_CP117668:1896818-1897144 [Escherichia albertii]
MHSEQWGLTCGKKPCFSARLVQEGNRLHFLADWAGFTGKFSNDEALRLDQAFPLIMKQLEQKLSAGELNSRRQQCVTLHH
IGLTCKADTLGSHGYLYIAIYPSATATG

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References