Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 799495..800273 Replicon chromosome
Accession NZ_CP117659
Organism Escherichia albertii strain BIA_13

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag PS034_RS03885 Protein ID WP_095576018.1
Coordinates 799785..800273 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag PS034_RS03880 Protein ID WP_095576019.1
Coordinates 799495..799788 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS034_RS03860 (795005) 795005..795628 + 624 WP_000889448.1 hypothetical protein -
PS034_RS03865 (795628) 795628..796866 + 1239 WP_273822520.1 hypothetical protein -
PS034_RS03870 (796863) 796863..797741 + 879 WP_044712664.1 DUF2220 family protein -
PS034_RS03875 (798057) 798057..799247 - 1191 WP_273783690.1 IS4-like element ISEc60 family transposase -
PS034_RS03880 (799495) 799495..799788 + 294 WP_095576019.1 DUF1778 domain-containing protein Antitoxin
PS034_RS03885 (799785) 799785..800273 + 489 WP_095576018.1 GNAT family N-acetyltransferase Toxin
PS034_RS03890 (800557) 800557..800895 - 339 WP_273822523.1 hypothetical protein -
PS034_RS03895 (801106) 801106..801357 - 252 WP_095576016.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 798057..799247 1190


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(74-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17654.52 Da        Isoelectric Point: 8.5163

>T271921 WP_095576018.1 NZ_CP117659:799785-800273 [Escherichia albertii]
MISAPEPLHAGHVLTSFCCGVDSMDNWLKQRAMKNQVTGASRTFVCCDNNSKVRAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDKSLHGQGIGRALMRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLV
HA

Download         Length: 489 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10782.41 Da        Isoelectric Point: 10.5480

>AT271921 WP_095576019.1 NZ_CP117659:799495-799788 [Escherichia albertii]
MPAANSLSIKRETLNLRIKPAERALIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMTDPDAYQAFLARLDQAPAPN
AALRKTMQTPAPWEQNK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References