Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 702177..703012 Replicon chromosome
Accession NZ_CP117647
Organism Escherichia albertii strain BIA_16-3

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag PS048_RS03450 Protein ID WP_001685371.1
Coordinates 702635..703012 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag PS048_RS03445 Protein ID WP_003986733.1
Coordinates 702177..702545 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PS048_RS03420 (699596) 699596..699829 + 234 WP_064986988.1 DUF905 family protein -
PS048_RS03425 (699920) 699920..700738 + 819 WP_097331407.1 DUF932 domain-containing protein -
PS048_RS03430 (700830) 700830..701315 + 486 WP_256917577.1 antirestriction protein -
PS048_RS03435 (701331) 701331..701807 + 477 WP_001366855.1 RadC family protein -
PS048_RS03440 (701876) 701876..702097 + 222 WP_000692353.1 DUF987 domain-containing protein -
PS048_RS03445 (702177) 702177..702545 + 369 WP_003986733.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PS048_RS03450 (702635) 702635..703012 + 378 WP_001685371.1 TA system toxin CbtA family protein Toxin
PS048_RS03455 (703009) 703009..703497 + 489 WP_001685372.1 DUF5983 family protein -
PS048_RS03460 (703509) 703509..703685 + 177 WP_001684188.1 DUF957 domain-containing protein -
PS048_RS03465 (703791) 703791..704636 + 846 WP_256917573.1 DUF4942 domain-containing protein -
PS048_RS03475 (704937) 704937..705443 + 507 WP_000245810.1 G/U mismatch-specific DNA glycosylase -
PS048_RS03480 (705523) 705523..707364 - 1842 WP_000437385.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14321.41 Da        Isoelectric Point: 9.2433

>T271846 WP_001685371.1 NZ_CP117647:702635-703012 [Escherichia albertii]
MKTLPDTLVREASRCPSPVTIWQTLLSRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPRF
STCPRSQLINSIDILRARRATGLMTRDNYRTVNNITRGKHPEAKR

Download         Length: 378 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13600.35 Da        Isoelectric Point: 6.3159

>AT271846 WP_003986733.1 NZ_CP117647:702177-702545 [Escherichia albertii]
VSDTLPGTTHPDDNNDRPWWGLPCTVTSCFGARLVQEGNRLHYLADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCEADTLGSCGYVYMAVYPTPETKK

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References